⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657260 | 0.77 | — | — | |
| SCHEMBL24843318 | 0.68 | — | — | |
| SCHEMBL20155269 | 0.65 | F2RL1 (0.31) | — | |
| SCHEMBL16739069 | 0.63 | L3MBTL1 (0.43) | — | |
| SCHEMBL18499545 | 0.63 | ALDH1A1 (0.33) | — | |
| SCHEMBL1445945 | 0.61 | PLAU (0.52) | — | |
| SCHEMBL12513707 | 0.60 | PIK3CB (0.30) | — | |
| SCHEMBL19663854 | 0.60 | — | — | |
| SCHEMBL19663716 | 0.59 | GRM2 (0.32) | — | |
| SCHEMBL23125736 | 0.58 | HSD17B10 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234554-A2 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | Incyte Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3472157-B1 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | INCYTE CORP (US) | 2023-04-12 | — | — | EP | disclosed |
| US-11377446-B2 | Crystalline solid forms of a BET inhibitor | INCYTE CORPORATION (US) | 2022-07-05 | — | — | US | disclosed |
| US-11091480-B2 | Crystalline solid forms of a BET inhibitor | INCYTE CORPORATION (US) | 2021-08-17 | — | — | US | disclosed |
| US-20210105998-A1 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | INCYTE CORPORATION | 2021-04-15 | — | — | US | disclosed |
| US-20200283436-A1 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | INCYTE CORPORATION | 2020-09-10 | — | — | US | disclosed |
| US-10626114-B2 | Crystalline solid forms of a BET inhibitor | INCYTE CORPORATION (US) | 2020-04-21 | — | — | US | disclosed |
| US-20190169186-A1 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | INCYTE CORPORATION | 2019-06-06 | — | — | US | disclosed |
| US-10189832-B2 | Crystalline solid forms of a BET inhibitor | INCYTE CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170362229-A1 | CRYSTALLINE SOLID FORMS OF A BET INHIBITOR | INCYTE CORPORATION | 2017-12-21 | — | — | US | disclosed |