Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083207 | 0.85 | PIK3CB (0.30) | PIK3CB | |
| SCHEMBL3989639 | 0.85 | PIK3CB (0.30) | PIK3CB | |
| SCHEMBL19100879 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL16439846 | 0.79 | CHRNB2 (0.34) | — | |
| SCHEMBL20155269 | 0.74 | F2RL1 (0.31) | — | |
| SCHEMBL31083085 | 0.74 | PIK3CB (0.35) | PIK3CB | |
| SCHEMBL20154949 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL30219113 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL13994243 | 0.67 | MGLL (0.35) | — | |
| SCHEMBL30702049 | 0.67 | NFATC1 (0.36) | PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638568-B1 | INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC N-SUBSTITUTED PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2011-07-27 | — | — | EP | disclosed |