Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020903 | 0.90 | PRSS1 (0.61) | NPC1RAB9ASMN1; SMN2PRSS1CTSG | |
| SCHEMBL19728223 | 0.85 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL25779518 | 0.85 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL14297358 | 0.82 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2PRSS1CTSG | |
| SCHEMBL2466111 | 0.81 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL25752880 | 0.81 | PRSS1 (0.67) | NPC1RAB9ASMN1; SMN2PRSS1CTSG | |
| SCHEMBL4530808 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL19734509 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL1927649 | 0.77 | DRD2 (0.77) | NPC1RAB9ASMN1; SMN2DRD2DRD4 | |
| SCHEMBL8160658 | 0.76 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362283-A1 | NISIN-BASED COMPOUNDS AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362283-A1 | NISIN-BASED COMPOUNDS AND USE THEREOF IN THE TREATMENT OF BACTERIAL INFECTIONS | NISCH, VIP, NGLY1 | NPC1 703/4885RAB9A 3302/4885SMN1; SMN2 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.