Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465573 | 0.92 | PRSS1 (0.61) | RAB9APRSS1CTSGCTRB1CMA1 | |
| SCHEMBL12321811 | 0.83 | MEN1 (0.50) | MAPTPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL12335902 | 0.83 | LMNA (0.52) | RAB9AMAPTPRSS1CTSGCTRB1 | |
| SCHEMBL12321807 | 0.83 | ADRB2 (0.49) | RAB9AMAPTPRSS1CTSGCTRB1 | |
| SCHEMBL19734634 | 0.81 | NPC1 (0.54) | RAB9APRSS1CTSGCTRB1CMA1 | |
| SCHEMBL12335901 | 0.81 | RAB9A (0.52) | RAB9AMAPTPRSS1CTSGCTRB1 | |
| SCHEMBL28016790 | 0.81 | EGFR (0.41) | RAB9AMAPTKDM4EKMT2A | |
| SCHEMBL19728223 | 0.79 | RAB9A (0.58) | RAB9APRSS1CTSGCTRB1CMA1 | |
| SCHEMBL25779518 | 0.79 | RAB9A (0.58) | RAB9APRSS1CTSGCTRB1CMA1 | |
| SCHEMBL19315670 | 0.79 | NPC1 (0.51) | RAB9AMAPTNPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9441058-B2 | Procatalyst composition with substituted amide ester internal electron donor | W. R. Grace & Co.—Conn. (US) | 2016-09-13 | — | — | US | disclosed |
| EP-2545087-B1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | GRACE W R & CO (US) | 2016-06-22 | — | — | EP | disclosed |
| US-20140163184-A1 | Procatalyst Composition with Substituted Amide Ester Internal Electron Donor | W. R. GRACE & CO.-CONN. | 2014-06-12 | — | — | US | disclosed |
| US-8604144-B2 | Procatalyst composition with substituted amide ester internal electron donor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2545087-A1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | Dow Global Technologies LLC (US) | 2013-01-16 | — | — | EP | disclosed |
| US-20120322962-A1 | Procatalyst Composition with Substituted Amide Ester Internal Electron Donor | W. R. GRACE & CO.-CONN. | 2012-12-20 | — | — | US | disclosed |
| WO-2011106494-A1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |