SCHEMBL1973504

SCHEMBL1973504

COc1cc(OC)c2c(c1)OC(c1ccc(OC)c(O)c1)C(O)C2

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.80
MAPK1 P28482 3/20 0.80
ABCB1 P08183 2/20 0.70
CYP19A1 P11511 1/20 0.53
BACE1 P56817 4/20 0.52
KDM4E B2RXH2 4/20 0.52
MAPT P10636 3/20 0.52
PTGS1 P23219 3/20 0.52
GAA P10253 3/20 0.52
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 2/20 0.52
PKM P14618 2/20 0.52
KMT2A Q03164 2/20 0.52
HSD17B10 Q99714 2/20 0.52
APEX1 P27695 2/20 0.52
RECQL P46063 2/20 0.52
ALPL P05186 2/20 0.52
POLB P06746 2/20 0.52
APP P05067 1/20 0.52
AMY1A P0DUB6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862416 0.94 CYP3A4 (0.78) CYP3A4MAPK1ABCB1BACE1KDM4E
SCHEMBL25246785 0.94 CYP3A4 (0.78) CYP3A4MAPK1ABCB1BACE1KDM4E
SCHEMBL1975181 0.93 CYP3A4 (0.68) CYP3A4MAPK1ABCB1BACE1KDM4E
SCHEMBL862097 0.93 CYP3A4 (0.68) CYP3A4MAPK1ABCB1BACE1KDM4E
SCHEMBL3805650 0.92 CYP3A4 (0.78) CYP3A4MAPK1ABCB1CYP19A1BACE1
SCHEMBL14691188 0.92 CYP3A4 (0.78) CYP3A4MAPK1ABCB1CYP19A1BACE1
Catechin Tetramethylether SCHEMBL30178011 0.91 CYP3A4 (0.81) CYP3A4MAPK1ABCB1MAPTALDH1A1
Catechin Tetramethylether SCHEMBL1430853 0.91 CYP3A4 (0.81) CYP3A4MAPK1ABCB1MAPTALDH1A1
Catechin Tetramethylether SCHEMBL30991591 0.91 CYP3A4 (0.81) CYP3A4MAPK1ABCB1MAPTALDH1A1
Catechin Tetramethylether SCHEMBL28731348 0.91 CYP3A4 (0.81) CYP3A4MAPK1ABCB1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210015964-A1 METHOD OF FORMING AND USING A HEMOSTATIC HYDROCOLLOID UNITED HEALTH PRODUCTS INC (US) 2021-01-21 US disclosed
US-20140046277-A1 FAST-CLOTTING WOUND DRESSINGS GAMMA THERAPEUTICS, INC. 2014-02-13 US disclosed
US-8557874-B2 Hemostatic material EPIC WOUND CARE, INC. (US) 2013-10-15 US disclosed
WO-2012142317-A1 FAST-CLOTTING WOUND DRESSINGS GAMMA THERAPEUTICS, INC (US) 2012-10-18 WO disclosed
EP-1803473-B1 Adhesive including medicament UNIV LOMA LINDA MED (US) 2011-06-22 EP disclosed
WO-2009070684-A2 HEMOSTATIC MATERIAL BAGGETT RICHARD W (US) 2009-06-04 WO disclosed
US-20090136562-A1 Hemostatic Material UNITED ECOENERGY CORP. 2009-05-28 US disclosed
WO-2009002768-A2 LIQUID BANDAGE MEDSPRING GROUP, INC. (US) 2008-12-31 WO disclosed
US-20080031929-A1 LIQUID BANDAGE MEDSPRING GROUP, INC. 2008-02-07 US disclosed
EP-1803473-A2 Adhesive including medicament Loma Linda University Medical Center (US) 2007-07-04 EP disclosed
US-20070026052-A1 Hemostatic material UNITED ECOENERGY CORP. 2007-02-01 US disclosed
US-20050123588-A1 Deployable multifunctional hemostatic agent LOMA LINDA UNIVERSITY MEDICAL CENTER 2005-06-09 US disclosed
US-20030044380-A1 Adhesive including medicament LOMA LINDA UNIVERSITY 2003-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044380-A1 Adhesive including medicament ICAM1, VCAM1, EPCAM CYP3A4 4815/4885MAPK1 4331/4885ABCB1 520/4885
US-20080031929-A1 LIQUID BANDAGE FGB, F2, F8 CYP3A4 3316/4885MAPK1 4222/4885ABCB1 3964/4885
US-20050123588-A1 Deployable multifunctional hemostatic agent FGB, CHIT1, CHIA CYP3A4 3864/4885MAPK1 4055/4885ABCB1 4815/4885
US-20070026052-A1 Hemostatic material F2, F8, F3 CYP3A4 2679/4885MAPK1 4199/4885ABCB1 4279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.