SCHEMBL19735296

SCHEMBL19735296

CC1(C)c2ccccc2-c2ccc3c4ccccc4n(C(C)(C)C)c3c21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.33
IDO1 P14902 1/20 0.33
DUSP3 P51452 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609835 0.82 ALKBH5 (0.49) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL21763048 0.81 ALKBH5 (0.34) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL24403669 0.81 ALKBH5 (0.34) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL18589649 0.80 DUSP3 (0.39) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL18589648 0.78 DUSP3 (0.38) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL17245709 0.78 KDM4E (0.41) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL10014056 0.78 KDM4E (0.45) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL14928107 0.78 APP (0.33)
SCHEMBL17245711 0.76 KDM4E (0.39) HSP90AA1IDO1DUSP3ALKBH5FTO
SCHEMBL17245641 0.76 MEN1 (0.40) HSP90AA1IDO1DUSP3ALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542258-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-01-03 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542258-B2 Heterocyclic compound and organic light emitting device comprising the same CYP1A1, CRY1, CYP1B1 HSP90AA1 4568/4885IDO1 698/4885DUSP3 4833/4885
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, NR2E3, LEF1 HSP90AA1 1987/4885IDO1 3225/4885DUSP3 4162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.