SCHEMBL19735543

SCHEMBL19735543

c1ccc(-c2ccc(N(c3ccc(-c4cccc5c4sc4ccccc45)cc3)c3ccc(C4(c5ccccc5)c5ccccc5C5(c6ccccc6)c6ccccc6-c6cccc4c65)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
OPRK1 P41145 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PARP14 Q460N5 1/20 0.32
PRKDC P78527 1/20 0.31
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19735547 0.97 ALOX5 (0.41) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804847 0.96 ALOX5 (0.43) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17126543 0.96 ALOX5 (0.43) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804854 0.94 ALOX5 (0.43) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804853 0.94 ALOX5 (0.45) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804840 0.94 ALOX5 (0.45) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804848 0.93 ALOX5 (0.44) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17903162 0.93 ALOX5 (0.44) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804662 0.92 ALOX5 (0.44) ALOX5KDM4EMEN1LMNAMAPT
SCHEMBL17804814 0.92 ALOX5 (0.46) ALOX5KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3369719-B1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-02-26 EP disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, NR2E3, LEF1 ALOX5 2559/4885KDM4E 3359/4885MEN1 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.