Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973579 | 1.00 | MEN1 (0.53) | MEN1KMT2ACTDSP1SMN1; SMN2RAB9A | |
| SCHEMBL2617527 | 1.00 | MEN1 (0.53) | MEN1KMT2ACTDSP1SMN1; SMN2RAB9A | |
| SCHEMBL13925576 | 0.91 | MIF (0.49) | MEN1KMT2ACTDSP1SMN1; SMN2RAB9A | |
| SCHEMBL4304419 | 0.86 | MIF (0.45) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11928961 | 0.86 | MIF (0.45) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4305863 | 0.86 | MIF (0.45) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13499996 | 0.85 | PLA2G7 (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3384931 | 0.84 | LMNA (0.52) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6118220 | 0.84 | LMNA (0.52) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL687935 | 0.84 | LMNA (0.52) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865844-A | Continuous synthesis method of ethyl benzaminoacetate | 新疆兴发化工有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117865844-A | Continuous synthesis method of ethyl benzaminoacetate | 新疆兴发化工有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-11667631-B2 | FGFR4 inhibitor, preparation method therefor, and applications thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| CN-113461690-B | Synthesis method of chiral 4,6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylate compound | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |
| CN-109796353-B | Synthetic method of 5-aminolevulinic acid hydrochloride | 福建南方制药股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-113461690-A | Synthesis method of chiral 4, 6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylic ester compound | 中国科学院大连化学物理研究所 | 2021-10-01 | — | — | CN | disclosed |
| US-20190276451-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2019-09-12 | — | — | US | disclosed |
| CN-109796353-A | A kind of synthetic method of 5-aminoketoglutarate hydrochloride | 福建南方济民医药研发中心有限公司 | 2019-05-24 | — | — | CN | disclosed |
| EP-3444250-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2019-02-20 | — | — | EP | disclosed |
| EP-2586769-B1 | METHOD FOR PRODUCING (1R, 2S)-1-AMINO-2-VINYL CYCLOPROPANE CARBOXYLIC ACID ESTER THAT HAS IMPROVED OPTICAL PURITY | KANEKA CORP (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-4368157-A | ANTICONVULSANTS, MUSCLE RELAXANTS, TRANQUILIZERS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1983-01-11 | — | — | US | disclosed |
| US-4368158-A | ANTICONVULSANTS, MUSCLE RELAXANTS, TRANQUILIZERS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1983-01-11 | — | — | US | disclosed |
| EP-0068373-A1 | Schiff bases of aminocycloalcanecarboxylic esters, preparation thereof and use thereof as intermediate products | BASF Aktiengesellschaft (DE) | 1983-01-05 | — | — | EP | disclosed |
| US-4347365-A | ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347364-A | INTERMEDIATES THEREFOR | HOFFMANN-LA ROCHE INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4332958-A | Benzylidene glycine ester derivatives | ZOECON CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0047516-A1 | Propylamine derivative and process of manufacturing the same | TORAY INDUSTRIES, INC. (JP) | 1982-03-17 | — | — | EP | disclosed |
| US-4307237-A | ANTICONVULSANTS, SEDATIVES, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1981-12-22 | — | — | US | disclosed |
| US-4298760-A | Process for preparing 1-aminocyclopropane-1-carboxylic acid | ZOECON CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |
| US-4280957-A | Imidazodiazepines and processes therefor | HOFFMANN-LA ROCHE INC. (US) | 1981-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276451-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF | FGFR4, FGFR1, FGFR2 | MEN1 1112/4885KMT2A 2300/4885CTDSP1 2844/4885 |
| US-11667631-B2 | FGFR4 inhibitor, preparation method therefor, and applications thereof | FGFR4, FGFR1, FGFR2 | MEN1 1112/4885KMT2A 2300/4885CTDSP1 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.