Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118220 | 1.00 | LMNA (0.52) | LMNACA2CA1MEN1KMT2A | |
| SCHEMBL3384931 | 1.00 | LMNA (0.52) | LMNACA2CA1MEN1KMT2A | |
| SCHEMBL28360448 | 0.84 | LMNA (0.45) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29154325 | 0.84 | LMNA (0.45) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1973580 | 0.84 | MEN1 (0.53) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2617527 | 0.84 | MEN1 (0.53) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1973579 | 0.84 | MEN1 (0.53) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL23345343 | 0.83 | KMT2A (0.58) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL19020191 | 0.83 | HPGD (0.47) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1769121 | 0.83 | KMT2A (0.58) | MEN1KMT2ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924973-A | Preparation method of 3-chloro-2-aminomethyl-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| US-5380849-A | Process for optically pure decahydroisoqiunolines | MERCK & CO., INC. (US) | 1995-01-10 | — | — | US | claimed |
| WO-1994011345-A1 | PROCESS FOR OPTICALLY PURE DECAHYDROISOQUINOLINES | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | claimed |
| CN-117551025-A | Preparation method of 4, 4-dicyano-2-alkyl-pyrrolidine-2-carboxylic ester derivative | 华北水利水电大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-116924973-A | Preparation method of 3-chloro-2-aminomethyl-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116924973-A | Preparation method of 3-chloro-2-aminomethyl-5-trifluoromethyl pyridine hydrochloride | 天津均凯农业科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-113461690-B | Synthesis method of chiral 4,6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylate compound | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |
| CN-110577485-B | Norcamphor derived [2, 1] -bridged ring ketene compounds and synthesis method and application thereof | 武汉大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-114940661-A | Norcamphor derived [2,2,1] -bridged ketene compounds and synthesis method and application thereof | 武汉大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-113461690-A | Synthesis method of chiral 4, 6-dioxooctahydropyrrolo [3,4-c ] pyrrole-1-carboxylic ester compound | 中国科学院大连化学物理研究所 | 2021-10-01 | — | — | CN | disclosed |
| CN-110669046-B | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2021-07-06 | — | — | CN | disclosed |
| EP-0625987-A1 | AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMACEUTICALS INC. (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1994011345-A1 | PROCESS FOR OPTICALLY PURE DECAHYDROISOQUINOLINES | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | disclosed |
| WO-1993016103-A1 | AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-08-19 | — | — | WO | disclosed |
| EP-0534396-A2 | 2-Substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ace | MERRELL PHARMACEUTICALS INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0534492-A2 | Carboxyalkyl substituted inhibitors of enkephalinase and ACE | MERRELL PHARMACEUTICALS INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0534363-A2 | Novel 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace | MERRELL PHARMACEUTICALS INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0481522-A1 | Novel mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace | MERRELL PHARMACEUTICALS INC. (US) | 1992-04-22 | — | — | EP | disclosed |