Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19729139 | 0.80 | PTPN1 (0.38) | HMGCRALOX5NFKB1PTPN1 | |
| SCHEMBL19729137 | 0.78 | LDHA (0.37) | HMGCRALOX5PTGS1PTGS2PTPN1 | |
| SCHEMBL25186769 | 0.75 | HMGCR (0.41) | HMGCRALOX5ERN1 | |
| SCHEMBL31507904 | 0.72 | ALOX5 (0.42) | ALOX5STAT3NFE2L2PTGESPTGS1 | |
| SCHEMBL7114104 | 0.71 | ALOX5 (0.53) | HMGCRALOX5PTGS2PTPN1 | |
| SCHEMBL18753168 | 0.70 | HMGCR (0.43) | HMGCRALOX5 | |
| SCHEMBL29814905 | 0.68 | ALOX5 (0.49) | ALOX5PTGS2ERN1 | |
| SCHEMBL27002072 | 0.68 | ALOX5 (0.49) | ALOX5PTGS2ERN1 | |
| SCHEMBL6233280 | 0.68 | ALOX5 (0.77) | HMGCRALOX5PTGS2 | |
| SCHEMBL19737045 | 0.68 | HMGCR (0.62) | HMGCRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362508-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | PBDC1, RCC1, PUF60 | HMGCR 2555/4885ALOX5 953/4885STAT3 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.