Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.56 |
| ▸ | FEN1 | P39748 | 16/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 16/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020144 | 0.83 | GRM5 (0.60) | GRM5FEN1ALOX5AP | |
| SCHEMBL22652321 | 0.81 | GRM5 (0.58) | GRM5FEN1ALOX5AP | |
| SCHEMBL11955018 | 0.78 | NNMT (0.48) | GRM5FEN1ALOX5AP | |
| SCHEMBL25636518 | 0.77 | NNMT (0.45) | GRM5FEN1ALOX5AP | |
| SCHEMBL12019744 | 0.77 | GRM5 (0.50) | GRM5FEN1ALOX5APIMPDH2 | |
| SCHEMBL19286094 | 0.75 | GRM5 (0.46) | GRM5FEN1ALOX5APIMPDH2 | |
| SCHEMBL24654855 | 0.75 | BACE1 (0.36) | GRM5 | |
| SCHEMBL14349440 | 0.75 | GRM5 (0.48) | GRM5FEN1ALOX5APIMPDH2 | |
| SCHEMBL12462535 | 0.74 | GRM5 (0.54) | GRM5FEN1ALOX5APIMPDH2 | |
| SCHEMBL91447 | 0.74 | GRM5 (0.54) | GRM5FEN1ALOX5APIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362180-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362180-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | GRM5 4193/4885FEN1 2761/4885ALOX5AP 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.