Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18607299 | 0.76 | TDP1 (0.35) | LMNATDP1 | |
| SCHEMBL19738033 | 0.74 | — | — | |
| SCHEMBL24974991 | 0.70 | TRPV1 (0.32) | — | |
| SCHEMBL10594780 | 0.69 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL20614516 | 0.67 | — | — | |
| SCHEMBL22674081 | 0.67 | — | — | |
| SCHEMBL20710573 | 0.67 | — | — | |
| Mannitol SCHEMBL27649816 | 0.65 | PDE4A (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL20698064 | 0.65 | — | — | |
| SCHEMBL20964080 | 0.65 | THRB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10307353-B2 | 1-phenylmono- or -polyhydroxypropane compounds, compositions and cosmetic uses thereof | L'OREAL (FR) | 2019-06-04 | — | — | US | disclosed |
| US-20170360665-A1 | NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10307353-B2 | 1-phenylmono- or -polyhydroxypropane compounds, compositions and cosmetic uses thereof | GLA, PAH, P4HA1 | LMNA 1322/4885L3MBTL1 3258/4885TDP1 111/4885 |
| US-20170360665-A1 | NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF | GLA, PAH, P4HA1 | LMNA 1755/4885L3MBTL1 3736/4885TDP1 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.