Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 5/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19738430 | 0.93 | AKR1B10 (0.42) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19730235 | 0.91 | THRB (0.43) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738421 | 0.90 | AKR1B10 (0.44) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738381 | 0.90 | AKR1B10 (0.44) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738194 | 0.90 | AKR1B10 (0.44) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738373 | 0.89 | AKR1B10 (0.41) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738284 | 0.85 | MET (0.41) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738395 | 0.84 | AKR1B10 (0.42) | THRBAKR1B10AKR1B1TSHRMET | |
| SCHEMBL19738415 | 0.83 | CA12 (0.44) | THRBAKR1B10AKR1B1HPGDTSHR | |
| SCHEMBL19738376 | 0.83 | AKR1B10 (0.39) | THRBAKR1B10AKR1B1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170364025-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE INCLUDING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-12-21 | — | — | US | disclosed |