Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879880 | 0.92 | ABCB1 (0.39) | MAOAACHEABCB1MAPTNPC1 | |
| SCHEMBL19389074 | 0.92 | ABCB1 (0.39) | MAOAACHEABCB1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL28631038 | 0.91 | ABCB1 (0.38) | MAOAACHEABCB1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL28631036 | 0.91 | ABCB1 (0.38) | MAOAACHEABCB1MAPTNPC1 | |
| SCHEMBL15134801 | 0.81 | ABCB1 (0.38) | MAOAACHEABCB1MAPTNPC1 | |
| SCHEMBL15947617 | 0.81 | MAOA (0.40) | MAOAACHEABCB1MAPTNPC1 | |
| SCHEMBL13108073 | 0.80 | ABCB1 (0.38) | MAOAACHEABCB1MAPTNPC1 | |
| SCHEMBL10042788 | 0.80 | RAB9A (0.52) | ABCB1MAPTNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL20529546 | 0.79 | RAB9A (0.54) | ABCB1MAPTNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL20529544 | 0.79 | RAB9A (0.54) | ABCB1MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362259-A1 | PROCESS AND INTERMEDIATES FOR MAKING TUBULYSIN ANALOGS | BRISTOL-MYERS SQUIBB COMPANY | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362259-A1 | PROCESS AND INTERMEDIATES FOR MAKING TUBULYSIN ANALOGS | NGLY1, TEK, MAN2B2 | MAOA 3373/4885ACHE 4445/4885ABCB1 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.