Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666107 | 0.93 | MAPT (0.39) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL28319649 | 0.93 | MAPT (0.39) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL14773338 | 0.93 | MAPT (0.39) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL2804328 | 0.84 | KDM4E (0.39) | ALDH1A1FAAHSMN1; SMN2TSHR | |
| SCHEMBL6429282 | 0.83 | MAPT (0.43) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL4251857 | 0.83 | MAPT (0.43) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL6435481 | 0.81 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNAFAAH | |
| Hydrochloric Acid SCHEMBL2425645 | 0.81 | MAPT (0.42) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL629450 | 0.80 | ALDH1A1 (0.42) | MAPTABCC4ALDH1A1LMNAFAAH | |
| SCHEMBL7940508 | 0.79 | FAAH (0.56) | MAPTLMNAFAAHSMN1; SMN2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110357-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) | University of Georgia Research Foundation, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| US-10188691-B2 | Protein interfaces | SYNTHEX, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170368132-A1 | PROTEIN INTERFACES | SYNTHEX, INC. | 2017-12-28 | — | — | US | disclosed |