Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448231 | 0.97 | ALDH1A1 (0.36) | ALDH1A1TDP1DNM1TSHRCYP3A4 | |
| SCHEMBL1971485 | 0.92 | OPRM1 (0.44) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28153724 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28161032 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28361753 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28271638 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28154751 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL1968956 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28154740 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA | |
| SCHEMBL28153736 | 0.90 | OPRM1 (0.42) | DNM1TSHROPRM1CA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510500-A | Preparation method of asperazepanones alkaloid and application of asperazepanones alkaloid as anti-inflammatory drug | 中国海洋大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-117050043-A | 3-phenyl dibenzofuran compound and preparation method and application thereof | 中国海洋大学 | 2023-11-14 | — | — | CN | disclosed |
| US-20230310419-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-10-05 | — | — | US | disclosed |
| CN-116726010-A | Application of macrolide derivative in preparation of medicines for inhibiting pro-inflammatory cytokine acting agents | 中国海洋大学 | 2023-09-12 | — | — | CN | disclosed |
| EP-4180041-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | Mayo Foundation for Medical Education and Research (US) | 2023-05-17 | — | — | EP | disclosed |
| US-11596629-B2 | Compounds and methods for treating cancer | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-03-07 | — | — | US | disclosed |
| CN-112851622-B | Macrolide brefeldin A ester derivative and application thereof | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |
| US-20220411389-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2022-12-29 | — | — | US | disclosed |
| US-11325892-B2 | Compounds and methods for treating cancer | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2022-05-10 | — | — | US | disclosed |
| US-11156619-B2 | Fluorescent pH sensors and methods of preparing them | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-10-26 | — | — | US | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |
| CN-1040982-A | Nitragin (rhizoxin) derivative and as antineoplastic agent | SANKYO CO (JP) | 1990-04-04 | — | — | CN | disclosed |
| CN-1040196-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO CO (JP) | 1990-03-07 | — | — | CN | disclosed |
| EP-0353047-A2 | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | Sankyo Company Limited (JP) | 1990-01-31 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4791128-A | Rhizoxin esters and salts, their pharmaceutical use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1988-12-13 | — | — | US | disclosed |
| US-4683224-A | INSECTICIDES, MITICIDES, NEMATOCIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| CN-86106331-A | N-formyl radical sulfo-phosphonic amide ester | — | 1987-06-03 | — | — | CN | disclosed |
| EP-0218310-A2 | Rhizoxin derivatives, their preparation and pharmaceutical use | SANKYO COMPANY LIMITED (JP) | 1987-04-15 | — | — | EP | disclosed |
| CN-86102020-A | The preparation method of rhizoxin derivatives and in pharmaceutically application | — | 1986-10-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11325892-B2 | Compounds and methods for treating cancer | SCD, CPT1B, CPT1A | ALDH1A1 287/4885TDP1 1349/4885DNM1 728/4885 |
| US-11156619-B2 | Fluorescent pH sensors and methods of preparing them | PHF8, PHF6, H1-0 | ALDH1A1 403/4885TDP1 1659/4885DNM1 737/4885 |
| US-20220411389-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | SCD, CPT1B, CPT1A | ALDH1A1 287/4885TDP1 1349/4885DNM1 728/4885 |
| US-11596629-B2 | Compounds and methods for treating cancer | SCD, SCD5, CPT1B | ALDH1A1 255/4885TDP1 877/4885DNM1 1277/4885 |
| US-20230310419-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | SCD, SCD5, CPT1B | ALDH1A1 255/4885TDP1 877/4885DNM1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.