Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.39 |
| ▸ | KDM5C | P41229 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741636 | 1.00 | KDM4C (0.40) | KDM4CHPGDKDM5BKDM5CKDM6B | |
| SCHEMBL17144518 | 0.73 | TRPV3 (0.50) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL17144520 | 0.73 | TRPV3 (0.50) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL19664325 | 0.69 | KDM5B (0.44) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL16291524 | 0.69 | KDM5B (0.44) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL17144521 | 0.69 | KDM5B (0.45) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL19574371 | 0.68 | KDM5B (0.45) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL19549130 | 0.68 | KDM5B (0.47) | KDM4CKDM5BKDM5CKDM6BKDM4A | |
| SCHEMBL17144516 | 0.67 | ALDH1A1 (0.39) | KDM5BKDM5CKDM6BKDM4AKDM5A | |
| SCHEMBL16291806 | 0.67 | KDM5B (0.53) | KDM4CKDM5BKDM5CKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | claimed |
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369444-A1 | INHIBITORS OF HISTONE DEMETHYLASES | KDM1B, KDM3A, KDM1A | KDM4C 38/4885HPGD 717/4885KDM5B 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.