Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL31572073 | 1.00 | SLC6A9 (0.43) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| Oxalic Acid SCHEMBL31572072 | 1.00 | SLC6A9 (0.43) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL31543752 | 0.94 | SLC6A4 (0.43) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL31543768 | 0.94 | SLC6A4 (0.43) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL17880601 | 0.94 | SLC6A4 (0.43) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| Oxalic Acid SCHEMBL19742808 | 0.93 | SLC6A9 (0.44) | SLC6A9ALDH1A1SLC6A4HRH3KDM4E | |
| Oxalic Acid SCHEMBL31054153 | 0.93 | SLC6A9 (0.44) | SLC6A9ALDH1A1SLC6A4HRH3KDM4E | |
| Oxalic Acid SCHEMBL19742736 | 0.91 | AOC3 (0.38) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| Oxalic Acid SCHEMBL19742800 | 0.91 | UTS2R (0.48) | SLC6A9UTS2R | |
| Paraben SCHEMBL31572075 | 0.90 | SLC6A9 (0.39) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093644-B2 | 3-[(Benzo[D][1,3]dioxolan-4-yl)-oxy]-3-arylpropylamine type compounds and applications thereof | NHWA PHARMA. CORPORATION (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20170369466-A1 | 3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND APPLICATIONS THEREOF | NHWA PHARMA. CORPORATION (CN) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10093644-B2 | 3-[(Benzo[D][1,3]dioxolan-4-yl)-oxy]-3-arylpropylamine type compounds and applications thereof | TPH1, MAOA, MAOB | SLC6A4 7/4885SLC6A9 552/4885ALDH1A1 89/4885 |
| US-20170369466-A1 | 3-[(BENZO[D][1,3]DIOXOLAN-4-YL)-OXY]-3-ARYLPROPYLAMINE TYPE COMPOUNDS AND APPLICATIONS THEREOF | TPH1, MAOA, MAOB | SLC6A4 7/4885SLC6A9 552/4885ALDH1A1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.