SCHEMBL19742933

SCHEMBL19742933

N#Cc1[c]ccc(C#N)n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS2 Q07890 1/20 0.33
NQO1 P15559 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18300525 0.76
SCHEMBL4756829 0.76
SCHEMBL16741211 0.76
SCHEMBL17529618 0.75 NQO1 (0.42) SOS2NQO1
SCHEMBL17529647 0.67 NQO1 (0.33) NQO1
SCHEMBL17529613 0.67 CTSS (0.36) NQO1
SCHEMBL995983 0.64 SOS2 (0.50) SOS2NQO1
SCHEMBL18422446 0.63 CTSS (0.42) SOS2
SCHEMBL3950907 0.63 SOS2 (0.44) SOS2NQO1
SCHEMBL129622 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10582708-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative MITSUI CHEMICALS AGRO, INC. (JP) 2020-03-10 US disclosed
US-20170367329-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2017-12-28 US disclosed
CN-102764242-B Oral dosage form comprising a PDE 4 inhibitor as active ingredient and polyvinylpyrrolidone as excipient 塔科达有限责任公司 2016-09-07 CN disclosed
CN-102764242-A Oral dosage form comprising a PDE 4 inhibitor as active ingredient and polyvinylpyrrolidone as excipient ALTANA PHARMA AG 2012-11-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10582708-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative H1-2, H1-4, H1-0 SOS2 3152/4885NQO1 594/4885
US-20170367329-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 SOS2 3152/4885NQO1 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.