Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20264922 | 0.72 | NQO1 (0.38) | SOS2NQO1 | |
| SCHEMBL1071858 | 0.71 | CYP1A2 (0.46) | — | |
| SCHEMBL16049760 | 0.69 | — | — | |
| SCHEMBL3955189 | 0.69 | CYP2A6 (0.33) | — | |
| SCHEMBL4358400 | 0.69 | METAP2 (0.31) | — | |
| SCHEMBL4851470 | 0.69 | CYP3A4 (0.30) | — | |
| SCHEMBL3282411 | 0.69 | NCF1 (0.45) | — | |
| SCHEMBL75226 | 0.67 | GRM5 (0.53) | SOS2SRCNQO1 | |
| SCHEMBL29359679 | 0.67 | GRM5 (0.53) | SOS2SRCNQO1 | |
| SCHEMBL27416745 | 0.67 | GRM5 (0.53) | SOS2SRCNQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
| US-7507732-B2 | Cyclopentapyridine and tetrahydroquinoline derivatives | PFIZER INC. (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060247254-A1 | Cyclopentapyridine and tetrahydroquinoline derivatives | PFIZER. INC | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131444-A1 | Aminopiperidine Quinolines and Their Azaisosteric Analogues with Antibacterial Activity | AAAS, AMPD2, AMPD3 | SOS2 4496/4885SRC 3966/4885NQO1 578/4885 |
| US-20060247254-A1 | Cyclopentapyridine and tetrahydroquinoline derivatives | HTR2C, HTR2A, HTR5A | SOS2 1651/4885SRC 3892/4885NQO1 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.