SCHEMBL995983

SCHEMBL995983

N#Cc1cccc(C#N)n1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SOS2 Q07890 1/20 0.50
CTSK P43235 1/20 0.47
CTSS P25774 1/20 0.46
SRC P12931 1/20 0.39
AHR P35869 1/20 0.39
NQO1 P15559 1/20 0.38
IDH1 O75874 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NPY5R Q15761 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169469 0.87 SOS2 (0.42) SOS2CTSKCTSSSRCAHR
SCHEMBL29988787 0.86 CTSS (0.55) SOS2CTSKCTSSIDH1KDM4E
SCHEMBL9220648 0.86 CTSS (0.55) SOS2CTSKCTSSIDH1KDM4E
SCHEMBL1771966 0.84 CTSS (0.53) SOS2CTSKCTSSIDH1KDM4E
SCHEMBL23085539 0.83 SOS2 (0.40) SOS2CTSKCTSSKDM4EALDH1A1
SCHEMBL506943 0.82
SCHEMBL938230 0.82
SCHEMBL129516 0.82
SCHEMBL12300275 0.82
SCHEMBL17796259 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040440-A Chiral pyridine bisoxazoline ligand modified by pyridine ring C4-position alkyl derivative, and synthetic method and application thereof 华东师范大学 2025-05-27 CN claimed
CN-119213579-A Electrolyte composition for lithium ion battery cells having anodes comprising a blend of silicon-carbon composite particles and graphite particles 新罗纳米技术有限公司 2024-12-27 CN claimed
EP-4470058-A1 ELECTROLYTES FOR LITHIUM-ION BATTERY CELLS WITH NITRILE ADDITIVES Sila Nanotechnologies Inc. (US) 2024-12-04 EP claimed
US-20240297337-A1 LITHIUM-ION BATTERIES COMPRISING HIGH LITHIUM-DENSITY SUPPLEMENTAL CATHODE ACTIVE MATERIAL SILA NANOTECHNOLOGIES, INC. 2024-09-05 US claimed
CN-116037184-B Mild ammonia synthesis method and hydrogenation catalyst 山东大学 2024-08-16 CN claimed
CN-117945995-A Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof 中国科学院青海盐湖研究所 2024-04-30 CN claimed
CN-117924723-A Preparation method and application of single-atom-loaded covalent triazine frame nanosheets 西湖大学 2024-04-26 CN claimed
CN-114768849-B Preparation method and application of lamellar sulfur-doped carbon-nitrogen copolymer 浙江工业大学 2024-01-09 CN claimed
CN-115106093-B Preparation method and application of metal covalent organic framework catalyst 中科澜荷(山东)新材料有限责任公司 2023-12-22 CN claimed
US-20230299362-A1 ELECTROLYTE COMPOSITIONS FOR LITHIUM-ION BATTERY CELLS WITH ANODES COMPRISING A BLEND OF SILICON-CARBON COMPOSITE PARTICLES AND GRAPHITE PARTICLES SILA NANOTECHNOLOGIES, INC. 2023-09-21 US claimed
US-8362156-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2013-01-29 US claimed
US-8314189-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2012-11-20 US claimed
EP-2456555-A1 METHOD FOR OXIDIZING METHANE Studiengesellschaft Kohle MbH (DE) 2012-05-30 EP claimed
US-20120130071-A1 METHOD FOR OXIDIZING METHANE STUDIENGESELLSCHAFT KOHLE MBH (DE) 2012-05-24 US claimed
WO-2011009429-A1 METHOD FOR OXIDIZING METHANE STUDIENGESELLSCHAFT KOHLE MBH (DE) 2011-01-27 WO claimed
US-20100280217-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-11-04 US claimed
EP-2203482-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS Bridgestone Corporation (JP) 2010-07-07 EP claimed
WO-2009051702-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-04-23 WO claimed
WO-2009051700-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (US) 2009-04-23 WO claimed
US-20090099325-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION 2009-04-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130071-A1 METHOD FOR OXIDIZING METHANE TST, MGMT, PMS2 SOS2 77/4885CTSK 4644/4885CTSS 4050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.