SCHEMBL197434

SCHEMBL197434

Cn1ccnc1-c1cccc(-c2nccn2C)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.47
HTR2A P28223 1/20 0.47
BRD4 O60885 1/20 0.45
KDM4E B2RXH2 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CCNC P24863 2/20 0.41
CDK8 P49336 2/20 0.41
CCR1 P32246 2/20 0.40
CCR8 P51685 2/20 0.40
LPO P22079 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
ALPL P05186 1/20 0.40
HSP90AA1 P07900 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7172386 0.98 HTR2C (0.46) HTR2CHTR2ABRD4KDM4EL3MBTL1
Hydrochloric Acid SCHEMBL7179318 0.98 HTR2C (0.46) HTR2CHTR2ABRD4KDM4EL3MBTL1
Hydrochloric Acid SCHEMBL7175653 0.98 HTR2C (0.46) HTR2CHTR2ABRD4KDM4EL3MBTL1
Hydrochloric Acid SCHEMBL7173179 0.98 HTR2C (0.46) HTR2CHTR2ABRD4KDM4EL3MBTL1
Hydrochloric Acid SCHEMBL7176249 0.98 HTR2C (0.46) HTR2CHTR2ABRD4KDM4EL3MBTL1
Hydrochloric Acid SCHEMBL7171164 0.98 HTR2C (0.46) HTR2CHTR2ABRD4KDM4EL3MBTL1
SCHEMBL4109690 0.90 CCR1 (0.54) HTR2CHTR2ABRD4KDM4EL3MBTL1
SCHEMBL12877216 0.87 HTR2C (0.42) HTR2CHTR2ABRD4KDM4EL3MBTL1
SCHEMBL5265171 0.87 HTR2C (0.42) HTR2CHTR2ABRD4KDM4EL3MBTL1
SCHEMBL12075550 0.84 KDM4E (0.40) HTR2CHTR2ABRD4KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116601303-A Analyte sensor with metal-containing redox mediator and method of use thereof 雅培糖尿病护理公司 2023-08-15 CN disclosed
WO-2022147496-A1 ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME ABBOTT DIABETES CARE INC. (US) 2022-07-07 WO disclosed
US-20220202326-A1 ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME ABBOTT DIABETES CARE INC. (US) 2022-06-30 US disclosed
US-11233205-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-25 US disclosed
US-20190189939-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-06-20 US disclosed
EP-2920186-B1 NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION UNIV HONG KONG (CN) 2018-06-27 EP disclosed
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-9559321-B2 Metal complexes for use as dopants and other uses ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2017-01-31 US disclosed
US-20040054267-A1 Small volume in vitro analyte sensor THERASENSE, INC. 2004-03-18 US disclosed
US-20030199744-A1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. (US) 2003-10-23 US disclosed
US-6618934-B1 Method of manufacturing small volume in vitro analyte sensor THERASENSE, INC. 2003-09-16 US disclosed
US-6592745-B1 Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care THERASENSE, INC. 2003-07-15 US disclosed
US-6591125-B1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. 2003-07-08 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
EP-1119637-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR Therasense, Inc. (US) 2001-08-01 EP disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190189939-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSTC HTR2C 3191/4885HTR2A 4017/4885BRD4 1525/4885
US-20220202326-A1 ANALYTE SENSORS WITH METAL-CONTAINING REDOX MEDIATORS AND METHODS OF USING THE SAME GPX4, LPO, PRDX3 HTR2C 4499/4885HTR2A 4076/4885BRD4 3355/4885
US-11233205-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSTC HTR2C 3191/4885HTR2A 4017/4885BRD4 1525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.