Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.45 |
| ▸ | NCK1 | P16333 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 8/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25206895 | 0.77 | CRHBP (0.38) | DYRK1A | |
| SCHEMBL22338015 | 0.74 | CYP1A2 (0.45) | — | |
| SCHEMBL8628087 | 0.74 | PLAU (0.59) | BACE1NCK1PLAUNCF1NOS2 | |
| SCHEMBL20141123 | 0.73 | MAPK1 (0.31) | — | |
| SCHEMBL23777268 | 0.70 | PIM1 (0.39) | — | |
| SCHEMBL23554938 | 0.68 | TDP1 (0.31) | NOS2NOS3NOS1 | |
| SCHEMBL21672122 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL4443251 | 0.68 | CCR1 (0.43) | — | |
| SCHEMBL14830999 | 0.68 | NCF1 (0.37) | BACE1NCK1PLAUNCF1NOS2 | |
| SCHEMBL17608657 | 0.67 | MGAM (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111251-A1 | COMPOUNDS THAT INHIBIT POLO-LIKE KINASE 4 | EXELIXIS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| WO-2017220431-A1 | FUSED PYRAZOLE DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2017-12-28 | — | — | WO | disclosed |