Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CPS1 | P31327 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19744269 | 1.00 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL21187112 | 0.90 | LMNA (0.44) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL19744050 | 0.90 | LMNA (0.44) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL29986171 | 0.90 | LMNA (0.44) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL19743723 | 0.80 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL19744159 | 0.80 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL9684084 | 0.78 | SMN1; SMN2 (0.49) | LMNAKMT2AMEN1HPGDMAPT | |
| SCHEMBL9684093 | 0.78 | SMN1; SMN2 (0.49) | LMNAKMT2AMEN1HPGDMAPT | |
| SCHEMBL19743750 | 0.78 | LMNA (0.42) | LMNAKMT2AMEN1HPGDCPS1 | |
| SCHEMBL19744219 | 0.78 | LMNA (0.42) | LMNAKMT2AMEN1HPGDCPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11485720-B2 | Anti-infective agents | UNIVERSITY OF DUNDEE (GB) | 2022-11-01 | — | — | US | disclosed |
| EP-3472141-B1 | ANTI-INFECTIVE AGENTS | UNIV DUNDEE (GB) | 2022-10-05 | — | — | EP | disclosed |
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2021-04-08 | — | — | US | disclosed |
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2021-04-08 | — | — | US | disclosed |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2019-07-25 | — | — | US | disclosed |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2019-07-25 | — | — | US | disclosed |
| EP-3472141-A1 | ANTI-INFECTIVE AGENTS | University Of Dundee (GB) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017221002-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2017-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485720-B2 | Anti-infective agents | C1R, RRS1, ARG1 | PDE4A 2551/4885PDE4B 2342/4885PDE4C 2746/4885 |
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | C1R, RRS1, ARG1 | PDE4A 2551/4885PDE4B 2342/4885PDE4C 2746/4885 |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | C1R, ARG1, MSR1 | PDE4A 2483/4885PDE4B 2206/4885PDE4C 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.