SCHEMBL19743929

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3575758	0.76	GRM5 (0.53)	MEN1KMT2AKDM4EALDH1A1GRM5
	SCHEMBL10256130	0.75	PLAU (0.46)	KMT2AKDM4EALDH1A1ATRPLAU
	SCHEMBL410727	0.73	ATR (0.58)	KMT2AKDM4EALDH1A1GRM5ATR
	SCHEMBL12186472	0.72	ATR (0.38)	ALDH1A1ATRTDP1PRKDCGABRP
	SCHEMBL1318334	0.72	GRM5 (0.51)	MEN1KMT2AALDH1A1GRM5ATR
	SCHEMBL2114667	0.72	ATR (0.38)	ALDH1A1ATRTDP1PRKDCGABRP
	SCHEMBL3868054	0.71	GABRP (0.41)	MEN1KMT2AGRM5ATRTDP1
	SCHEMBL13242155	0.71	GRM5 (0.42)	MEN1KMT2AKDM4EGRM5ATR
	SCHEMBL4253183	0.71	SIRT6 (0.47)	KDM4EALDH1A1LMNAATRPLAU
	SCHEMBL13346098	0.71	ATR (0.36)	MEN1KMT2AKDM4EGRM5ATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.