Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940443 | 0.75 | GRM2 (0.35) | CRBNGRM2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7766815 | 0.73 | CRBN (0.43) | CRBNL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL19744406 | 0.71 | CRBN (0.46) | CRBNL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL19744326 | 0.71 | CRBN (0.46) | CRBNL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL10865471 | 0.69 | CRBN (0.44) | CRBNL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL7767198 | 0.66 | CRBN (0.49) | CRBNL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL7764873 | 0.64 | CYP2C19 (0.41) | CRBNGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18541672 | 0.63 | MEN1 (0.48) | CRBNNPC1MAPTRAB9AATM | |
| SCHEMBL7766827 | 0.62 | CYP2C19 (0.39) | CRBNGAAGRM2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7765809 | 0.62 | EHMT2 (0.42) | CRBNL3MBTL1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561126-A | OXAPENAMS HAVING CHEMICAL STABILITY; ANTICARCINOGENIC AGENTS; LEUKEMIA | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-10-01 | — | — | US | disclosed |