Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13393462 | 0.93 | MTOR (0.43) | MTORPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1973014 | 0.89 | MTOR (0.48) | MTORMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL3132015 | 0.84 | POLB (0.50) | MTORPOLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16318710 | 0.84 | PTGES (0.45) | MTORMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL1974244 | 0.84 | MAPT (0.49) | POLBMEN1KMT2ASMN1; SMN2MMP2 | |
| SCHEMBL1969892 | 0.79 | DGAT1 (0.43) | MEN1KMT2AMMP2MMP9MMP8 | |
| SCHEMBL1970703 | 0.78 | DGAT1 (0.46) | POLBMEN1KMT2ASMN1; SMN2MMP2 | |
| SCHEMBL1972015 | 0.77 | MMP2 (0.44) | MEN1KMT2AHTTMMP2MMP9 | |
| SCHEMBL1974657 | 0.77 | DGAT1 (0.46) | MEN1KMT2ASMN1; SMN2MMP2MMP9 | |
| SCHEMBL1977175 | 0.77 | MMP2 (0.52) | MTORMEN1KMT2AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | claimed |