SCHEMBL19750

SCHEMBL19750

CC(=O)Oc1ccccc1C(=O)O[N+](=O)[O-]

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.63
HSD17B10 Q99714 6/20 0.59
KDM4E B2RXH2 4/20 0.59
LMNA P02545 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
TSHR P16473 2/20 0.57
PTGS1 P23219 2/20 0.57
ESR1 P03372 1/20 0.57
ITGB3 P05106 1/20 0.57
ITGA2B P08514 1/20 0.57
HMGB1 P09429 1/20 0.57
GGT1 P19440 1/20 0.57
BLM P54132 1/20 0.57
NAPRT Q6XQN6 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
MAPT P10636 3/20 0.52
HSP90AA1 P07900 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622344 0.81 PTGS2 (0.43) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL2865396 0.80 TSHR (0.43) PTGS2HSD17B10KDM4ELMNAALDH1A1
SCHEMBL15889886 0.80 PTGS2 (0.65) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL15889887 0.80 PTGS2 (0.85) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL789771 0.79 HSD17B10 (0.71) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL10705752 0.79 HSD17B10 (0.71) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL5988737 0.79 HSD17B10 (0.71) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL29669847 0.79 HSD17B10 (0.71) PTGS2HSD17B10KDM4ELMNACYP1A2
Aspirin SCHEMBL2782628 0.79 KDM4E (0.80) PTGS2HSD17B10KDM4ELMNACYP1A2
SCHEMBL4960087 0.79 KDM4E (0.57) PTGS2HSD17B10KDM4ELMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12480162-B2 Detection of metastatic disease and related methods THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-11-25 US claimed
EP-3463434-B1 IMMUNOTHERAPY FOR CANCER EXCOSO A S (CZ) 2024-12-25 EP claimed
US-20240122977-A1 COMPOSITIONS AND METHODS FOR PARENTERAL ADMINISTRATION OF THERAPEUTIC AGENTS EPICENTRX, INC. 2024-04-18 US claimed
EP-3419676-B1 ANTIMICROBIAL COMPOSITIONS AND USES THEREOF UNIV TEXAS (US) 2022-08-31 EP claimed
US-20220202838-A1 COMBINATIONAL THERAPIES FOR TREATMENT OF CANCER COMPRISING A BACTERIOCHLOROPHYLL DERIVATIVE MEMORIAL SLOAN-KETTERING CANCER CENTER 2022-06-30 US claimed
US-20210379087-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2021-12-09 US claimed
CN-113347969-A Composition for eliminating senescent cells 维也纳自然资源与生命科学大学 2021-09-03 CN claimed
US-20210252120-A1 IMMUNOTHERAPY FOR CANCER SOTIO a.s. (CZ) 2021-08-19 US claimed
US-20210085736-A1 IMMUNO-ONCOLYTIC MODIFIED VACCINIA TIAN TAN VIRUS AND METHODS OF TREATING CANCER THE UNIVERSITY OF HONG KONG (HK) 2021-03-25 US claimed
CN-112004545-A Immuno-oncolytic modified vaccinia Tiantan virus and methods of treating cancer 香港大学 2020-11-27 CN claimed
US-20140294765-A1 LSR ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER COMPUGEN LTD. (IL) 2014-10-02 US claimed
WO-2014154804-A1 PHARMACEUTICAL FORMULATION FOR USE IN THE TREATMENT AND/OR PREVENTION OF RESTENOSIS CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (C.H.U.V) (CH) 2014-10-02 WO claimed
EP-2756093-A2 C10RF32 ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER Compugen Ltd. (IL) 2014-07-23 EP claimed
EP-2744830-A1 LSR ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER Compugen Ltd. (IL) 2014-06-25 EP claimed
WO-2013114367-A9 C10RF32 ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER COMPUGEN LTD. (IL) 2014-04-24 WO claimed
WO-2013190555-A1 LSR ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER COMPUGEN LTD. (IL) 2013-12-27 WO claimed
WO-2013114367-A2 C10RF32 ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER COMPUGEN LTD. (IL) 2013-08-08 WO claimed
EP-0825866-A1 COMBINED PREPARATIONS WITH VASCULAR EFFECT CONTAINING DIHYDROPYRIDINES, ACETYLSALICYLIC ACID NITROESTERS AND VITAMINS BAYER AG (DE) 1998-03-04 EP claimed
CN-1144092-A Non-steroid anti-inflammatory agents capable of releasing nitric oxide, their preparing method and use CAI XIONG (CN) 1997-03-05 CN claimed
WO-1996034607-A1 COMBINED PREPARATIONS WITH VASCULAR EFFECT CONTAINING DIHYDROPYRIDINES, ACETYLSALICYLIC ACID NITROESTERS AND VITAMINS BAYER AKTIENGESELLSCHAFT (DE) 1996-11-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202838-A1 COMBINATIONAL THERAPIES FOR TREATMENT OF CANCER COMPRISING A BACTERIOCHLOROPHYLL DERIVATIVE VHL, MYADM, PPOX PTGS2 244/4885HSD17B10 2690/4885KDM4E 1600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.