Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434088 | 0.86 | POLB (0.75) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL10127537 | 0.84 | KMT2A (0.50) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL10112093 | 0.83 | MEN1 (0.45) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL10911381 | 0.74 | L3MBTL1 (0.76) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL10911385 | 0.74 | L3MBTL1 (0.76) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL30541729 | 0.72 | LMNA (0.57) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL20306165 | 0.72 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL13825505 | 0.71 | MEN1 (0.43) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL31126839 | 0.71 | L3MBTL1 (0.66) | ALDH1A1L3MBTL1POLBLMNAHSD17B10 | |
| SCHEMBL22098310 | 0.70 | PPARG (0.47) | CYP4F2CYP4A11ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849107-B2 | Compositions and methods for inhibiting cytochrome P450 | SEQUOIA PHARMACEUTICALS, INC. (US) | 2017-12-26 | — | — | US | disclosed |