Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22878266 | 0.68 | — | — | |
| SCHEMBL18180889 | 0.68 | MAPT (0.35) | TLR4 | |
| SCHEMBL22305507 | 0.60 | PKM (0.41) | TLR4 | |
| SCHEMBL16693956 | 0.57 | CHRM5 (0.35) | — | |
| SCHEMBL22783853 | 0.56 | TLR4 (0.31) | TLR4 | |
| SCHEMBL14932168 | 0.56 | M6PR (0.30) | — | |
| SCHEMBL10307511 | 0.56 | MAPK1 (0.42) | — | |
| SCHEMBL30174115 | 0.56 | MAPK1 (0.42) | — | |
| SCHEMBL28272103 | 0.55 | — | — | |
| SCHEMBL12149518 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260449-A1 | USE OF TRICYCLIC SESQUITERPENE LACTONES IN THE TREATMENT OF OBESITY AND RELATED DISEASES AND NON-THERAPEUTIC TREATABLE CONDITIONS | Neem Biotech Ltd. (GB) | 2017-12-27 | — | — | EP | disclosed |