Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9983033 | 0.84 | CYP19A1 (0.60) | CYP19A1P2RX4SRCKMT2AMEN1 | |
| SCHEMBL801717 | 0.81 | KDM4E (0.37) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL801440 | 0.81 | KDM4E (0.37) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL801102 | 0.81 | NPSR1 (0.34) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL801432 | 0.81 | NPSR1 (0.34) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL345810 | 0.81 | KDM4E (0.37) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL801300 | 0.78 | NPSR1 (0.35) | KMT2AMEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12879596 | 0.78 | NPSR1 (0.35) | KDM4ELMNAL3MBTL1 | |
| SCHEMBL23607253 | 0.77 | PSMD14 (0.48) | CYP19A1P2RX4SRCMAPTLMNA | |
| SCHEMBL17562120 | 0.76 | NPSR1 (0.33) | KMT2AMEN1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393819-B9 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | UDC IRELAND LTD (IE) | 2017-12-27 | — | — | EP | disclosed |