Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 9/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945159 | 1.00 | NQO2 (0.75) | NQO2MAPTRAB9APOLBNPC1 | |
| Sulfuric Acid SCHEMBL8431344 | 0.94 | NQO2 (0.80) | NQO2MAPTRAB9APOLBNPC1 | |
| Phenazine SCHEMBL8936740 | 0.91 | NQO2 (0.61) | NQO2MAPTRAB9APOLBNPC1 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL27551008 | 0.89 | NQO2 (0.77) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL31578887 | 0.87 | NQO2 (0.65) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL1513023 | 0.87 | NQO2 (1.00) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL27564424 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL28752582 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Ammonia Solution, Strong SCHEMBL27633219 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrogen Sulfide SCHEMBL28130030 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 719 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119464447-A | Detection reagent and detection method for isocitrate dehydrogenase activity | 北京中生金域诊断技术股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| EP-2994536-B1 | STABILIZATION OF ENZYMES BY NICOTINIC ACID | ROCHE DIABETES CARE GMBH (DE) | 2017-06-14 | — | — | EP | claimed |
| EP-2823052-B1 | COMPATIBLE SOLUTE ECTOINE AS WELL AS DERIVATIVES THEREOF FOR ENZYME STABILIZATION | ROCHE DIABETES CARE GMBH (DE) | 2016-10-26 | — | — | EP | claimed |
| US-20160108391-A1 | REAGENT COMPOSITIONS HAVING PYRIDINE-CARBOXYLIC ACID-STABILIZED ENZYMES, AS WELL AS METHODS OF MAKING AND USING THE SAME | ROCHE DIABETES CARE, INC. (US) | 2016-04-21 | — | — | US | claimed |
| EP-2994536-A1 | STABILIZATION OF ENZYMES BY NICOTINIC ACID | Roche Diagnostics GmbH (DE) | 2016-03-16 | — | — | EP | claimed |
| WO-2015160938-A1 | CONDUCTIVE INK COMPOSITIONS | Electroninks Incorporated (US) | 2015-10-22 | — | — | WO | claimed |
| EP-2823052-A1 | COMPATIBLE SOLUTE ECTOINE AS WELL AS DERIVATIVES THEREOF FOR ENZYME STABILIZATION | Roche Diagnostics GmbH (DE) | 2015-01-14 | — | — | EP | claimed |
| US-20140363835-A1 | COMPATIBLE SOLUTE ECTOINE AS WELL AS DERIVATIVES THEREOF FOR ENZYME STABILIZATION | ROCHE DIABETES CARE, INC. | 2014-12-11 | — | — | US | claimed |
| WO-2013131885-A1 | COMPATIBLE SOLUTE ECTOINE AS WELL AS DERIVATIVES THEREOF FOR ENZYME STABILIZATION | ROCHE DIAGNOSTICS GMBH (DE) | 2013-09-12 | — | — | WO | claimed |
| EP-2636750-A1 | Compatible solute ectoine as well as derivatives thereof for enzyme stabilization | Roche Diagniostics GmbH (DE) | 2013-09-11 | — | — | EP | claimed |
| WO-1993006487-A1 | REAGENTS AND ASSAY METHODS INCLUDING A PHENAZINE-CONTAINING INDICATOR | BOEHRINGER MANNHEIM CORPORATION (US) | 1993-04-01 | — | — | WO | claimed |
| EP-0496409-A1 | A method for the detection of gram-negative bacteria | ORION CORPORATION ORION DIAGNOSTICA (FI) | 1992-07-29 | — | — | EP | claimed |
| EP-0496410-A1 | A method for the detection of microorganisms | ORION CORPORATION ORION DIAGNOSTICA (FI) | 1992-07-29 | — | — | EP | claimed |
| EP-0296481-A2 | Method for the detection og gaseous material by means of an enzymatic redox-reaction | Drägerwerk Aktiengesellschaft (DE) | 1988-12-28 | — | — | EP | claimed |
| US-4683198-A | DOES NOT REQUIRE NAD OR NADP | TOYO JOZO KABUSHIKI KAISHA (JP) | 1987-07-28 | — | — | US | claimed |
| EP-0114267-B1 | TEST SYSTEM AND METHOD FOR THE DETERMINATION OF NAD(P)H | MERCK PATENT GmbH (DE) | 1986-06-25 | — | — | EP | claimed |
| EP-0114267-A1 | Test system and method for the determination of NAD(P)H | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | claimed |
| EP-0091911-A4 | GLUCOSE OXIDASE IMMUNOHISTOCHEMICAL DETECTION OF ANTINUCLEAR ANTIBODIES. | ICL SCIENT (US) | 1984-04-06 | — | — | EP | claimed |
| EP-0091911-A1 | GLUCOSE OXIDASE IMMUNOHISTOCHEMICAL DETECTION OF ANTINUCLEAR ANTIBODIES | ICL SCIENTIFIC (US) | 1983-10-26 | — | — | EP | claimed |
| WO-1983000877-A1 | GLUCOSE OXIDASE IMMUNOHISTOCHEMICAL DETECTION OF ANTINUCLEAR ANTIBODIES | ICL SCIENT (US) | 1983-03-17 | — | — | WO | claimed |