Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 9/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197530 | 1.00 | NQO2 (0.75) | NQO2MAPTRAB9APOLBNPC1 | |
| Sulfuric Acid SCHEMBL8431344 | 0.94 | NQO2 (0.80) | NQO2MAPTRAB9APOLBNPC1 | |
| Phenazine SCHEMBL8936740 | 0.91 | NQO2 (0.61) | NQO2MAPTRAB9APOLBNPC1 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL27551008 | 0.89 | NQO2 (0.77) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL31578887 | 0.87 | NQO2 (0.65) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL1513023 | 0.87 | NQO2 (1.00) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL27564424 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL28752582 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Ammonia Solution, Strong SCHEMBL27633219 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrogen Sulfide SCHEMBL28130030 | 0.85 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811692-B1 | METHOD OF DETERMINING BILE ACID CONJUGATED WITH SULFURIC ACID AND KIT THEREFOR | MARUKIN SHOYU KK (JP) | 2002-04-24 | — | — | EP | claimed |
| US-5919644-A | Method for assaying sulfate-conjugated bile acid and therefore | MARUKIN SHOYU CO., LTD. (JP) | 1999-07-06 | — | — | US | claimed |
| EP-0811692-A1 | METHOD OF DETERMINING BILE ACID CONJUGATED WITH SULFURIC ACID AND KIT THEREFOR | MARUKIN SHOYU CO., LTD. (JP) | 1997-12-10 | — | — | EP | claimed |
| JP-6209793-A | — | — | None | — | — | JP | disclosed |
| US-20240371475-A1 | ARTIFICIAL INTELLIGENCE-BASED EVALUATION OF DRUG EFFICACY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-07 | — | — | US | disclosed |
| CN-113476589-A | Use of peptides for the manufacture of a composition for the treatment of neurodegenerative diseases | 珍白斯凯尔有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-108431021-B | Peptide having neuron loss prevention and regeneration effects and composition comprising the same | 珍白斯凯尔有限公司 | 2021-09-07 | — | — | CN | disclosed |
| US-20180320217-A1 | METHODS FOR SAMPLING AND MEASURING ORAL LAVAGE PROTEINS | THE PROCTER & GAMBLE COMPANY | 2018-11-08 | — | — | US | disclosed |
| US-20180318383-A1 | PEPTIDE HAVING NEURONAL LOSS PREVENTION AND REGENERATION EFFECTS, AND COMPOSITION CONTAINING SAME | GEMVAX & KAEL CO., LTD. (KR) | 2018-11-08 | — | — | US | disclosed |
| EP-3372613-A1 | PEPTIDE HAVING NEURONAL LOSS PREVENTION AND REGENERATION EFFECTS, AND COMPOSITION CONTAINING SAME | Gemvax & Kael Co., Ltd. (KR) | 2018-09-12 | — | — | EP | disclosed |
| WO-2008090517-A2 | ENRICHED PLANT EXTRACT, COMPOUND, AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-07-31 | — | — | WO | disclosed |
| US-20040043376-A1 | Method and test strips for the measurement of fat loss during weight loss programs | GUPTA SURENDRA (US) | 2004-03-04 | — | — | US | disclosed |
| US-6569304-B1 | Planar open reference electrode for use in voltammeric measuring chains | SENSLAB GESELLSCHAFT ZUR ENTWICKLUNG UND HERSTELLUNG BIOELEKTROCHEMISCHER SENSOREN MBH (DE) | 2003-05-27 | — | — | US | disclosed |
| EP-0811692-B1 | METHOD OF DETERMINING BILE ACID CONJUGATED WITH SULFURIC ACID AND KIT THEREFOR | MARUKIN SHOYU KK (JP) | 2002-04-24 | — | — | EP | disclosed |
| EP-1045244-A1 | Planar open reference electrodes for use in voltammetric measuring systems | Senslab Gesellschaft zur Entwicklung und Herstellung Bioelektrochemischer Sensoren mbH (DE) | 2000-10-18 | — | — | EP | disclosed |
| US-5919644-A | Method for assaying sulfate-conjugated bile acid and therefore | MARUKIN SHOYU CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0811692-A1 | METHOD OF DETERMINING BILE ACID CONJUGATED WITH SULFURIC ACID AND KIT THEREFOR | MARUKIN SHOYU CO., LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| US-5624813-A | PEROXIDASES, OXIDOREDUCTASES | MAHANT, VIJAY K. | 1997-04-29 | — | — | US | disclosed |
| WO-1995029255-A1 | LUMINESCENCE-BASED DIAGNOSTICS | MEDILITE DIAGNOSTIKA (US) | 1995-11-02 | — | — | WO | disclosed |
| JP-H06209793-A | METHOD FOR MEASURING SORBITOL AND ITS COMPOSITION | TOYOBO CO LTD | 1994-08-02 | — | — | JP | disclosed |