Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 9/20 | 0.80 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945159 | 0.94 | NQO2 (0.75) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL197530 | 0.94 | NQO2 (0.75) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL1513023 | 0.89 | NQO2 (1.00) | NQO2MAPTRAB9APOLBNPC1 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL27551008 | 0.89 | NQO2 (0.77) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL28752582 | 0.88 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Ammonia Solution, Strong SCHEMBL27633219 | 0.88 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrogen Sulfide SCHEMBL28130030 | 0.88 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| Hydrochloric Acid SCHEMBL27564424 | 0.88 | NQO2 (0.96) | NQO2MAPTRAB9APOLBNPC1 | |
| SCHEMBL31578887 | 0.87 | NQO2 (0.65) | NQO2MAPTRAB9APOLBNPC1 | |
| Acetic Acid SCHEMBL28270696 | 0.87 | NQO2 (0.80) | NQO2MAPTRAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910450-A | FIXING AND HERMETICALLY SEALING ABSORPTION LAYER ONTO SURFACE USING ADHESIVE TAPE, DIFFUSION OR PENETRATION OF OBJECT EMMISSIONS TO LAYER; NONDESTRUCTIVE DETECTION OF POLLUTANTS FROM CONSTRUCTION MATERIALS, OFFICE FURNITURE, TEXTILES | DRAGERWERK AKTIENGESELLSCHAFT (DE) | 1999-06-08 | — | — | US | disclosed |
| US-4788141-A | BLOOD; HEPATITIS TESTING | MARUHO CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |