SCHEMBL197544

SCHEMBL197544

C[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
TSHR P16473 5/20 0.35
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
MAPT P10636 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040586 0.97 ESR1 (0.48) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL23211688 0.94 ESR1 (0.41) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL10319247 0.89 ESR1 (0.43) ESR1ESR2NR1H2NR1H3ACHE
SCHEMBL10319854 0.87 ACHE (0.46) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL1317182 0.83 MAPT (0.36) ESR1ESR2TSHRLMNAALOX12
SCHEMBL10318823 0.82 NR1H2 (0.43) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL10318939 0.82 ACHE (0.44) ESR1ESR2TSHRLMNAALOX12
SCHEMBL10320598 0.82 ALDH1A1 (0.46) ESR1ESR2TSHRLMNAMAPT
SCHEMBL10319284 0.82 CA4 (0.52) LMNAACHEALDH1A1TDP1KMT2A
SCHEMBL12815555 0.82 MEN1 (0.36) ESR1ESR2TSHRLMNAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2568 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137169-A High-crystallinity heat-conducting polysulfate and preparation method and application thereof 苏州工学院 2025-06-13 CN claimed
WO-2025061290-A1 PRODUCTION OF MONO-SUBSTITUTED HALOSILOXANES FROM CYCLOTRISILOXANES WACKER CHEMIE AG (DE) 2025-03-27 WO claimed
CN-118755090-A High-temperature-resistant easily-cured silicone resin and preparation method and application thereof 湖北硅元新材料科技有限公司 2024-10-11 CN claimed
CN-118666664-A Method for preparing p-methylbenzoic acid by catalyzing carbon dioxide and toluene 中国石油化工股份有限公司 2024-09-20 CN claimed
CN-118647215-A Perovskite battery, manufacturing method and electric equipment 宁德时代新能源科技股份有限公司 2024-09-13 CN claimed
CN-118359806-A Method for synthesizing polyamide by olefin carbonylation 西北大学 2024-07-19 CN claimed
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US claimed
CN-118271360-A Fluorinated phosphate, preparation method thereof, nonaqueous electrolyte containing fluorinated phosphate and electrochemical device 深圳市研一新材料有限责任公司 2024-07-02 CN claimed
CN-113698287-B Method for preparing p-methylbenzoic acid by catalyzing carbon dioxide and toluene 中国石油化工股份有限公司 2024-07-02 CN claimed
CN-117683234-A Low-cost fluorine-free silicon-based deepening agent and preparation method thereof 黄山市强力化工有限公司 2024-03-12 CN claimed
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO claimed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US claimed
EP-0461597-B1 Method for preparing monohalogenosilanes SHINETSU CHEMICAL CO (JP) 1995-03-01 EP claimed
US-5136070-A Sodium borohydride catalyzed disproportionation of cycloorganosilanes DOW CORNING CORPORATION (US) 1992-08-04 US claimed
US-5136071-A Reduces induction time DOW CORNING CORPORATION (US) 1992-08-04 US claimed
US-5110974-A Thermal disproportionation of arylhalosilanes DOW CORNING CORPORATION (US) 1992-05-05 US claimed
EP-0461597-A2 Method for preparing monohalogenosilanes Shin-Etsu Chemical Co., Ltd. (JP) 1991-12-18 EP claimed
EP-0419018-A2 Improvements in or relating to lithographic printing plates Du Pont (UK) Limited (GB) 1991-03-27 EP claimed
US-4481366-A Process for the preparation of a trifluorovinylsilane, and fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-11-06 US claimed
EP-0119404-A1 Fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-09-26 EP claimed