Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162935 | 0.86 | SLC6A4 (0.38) | NQO2MTNR1AMTNR1BSLC6A4HTR2A | |
| SCHEMBL1163145 | 0.81 | TAAR1 (0.42) | NQO2MTNR1AMTNR1BSLC6A4HTR2A | |
| SCHEMBL1163322 | 0.80 | TAAR1 (0.44) | NQO2MTNR1AMTNR1BSLC6A4HTR2A | |
| SCHEMBL1163481 | 0.77 | TAAR1 (0.40) | NQO2MTNR1AMTNR1BHTR2ATAAR1 | |
| SCHEMBL1162934 | 0.77 | TAAR1 (0.42) | NQO2MTNR1AMTNR1BHTR2ATAAR1 | |
| SCHEMBL1163355 | 0.76 | CARM1 (0.35) | NQO2MTNR1AMTNR1BSLC6A4HTR2A | |
| SCHEMBL1163043 | 0.75 | TAAR1 (0.39) | TAAR1SNCAMEN1KMT2A | |
| SCHEMBL19650679 | 0.74 | TAAR1 (0.40) | SLC6A4SLC6A2SLC6A3TAAR1SNCA | |
| SCHEMBL1163327 | 0.74 | TAAR1 (0.50) | SLC6A4HTR2ATAAR1ADRB2MEN1 | |
| SCHEMBL1163093 | 0.74 | TAAR1 (0.43) | NQO2MTNR1AMTNR1BSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION | 2011-06-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | NQO2 228/4885MTNR1A 65/4885MTNR1B 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.