Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659584 | 0.86 | AR (0.46) | PPARDPPARG | |
| SCHEMBL18838303 | 0.84 | VDR (0.48) | PPARDPPARG | |
| SCHEMBL2113005 | 0.84 | PTGDR2 (0.64) | PPARDPPARGPPARAPTGDR2TDP1 | |
| SCHEMBL1245338 | 0.83 | LMNA (0.50) | — | |
| SCHEMBL27535566 | 0.83 | MCL1 (0.53) | FFAR1 | |
| SCHEMBL3385737 | 0.82 | PPARD (0.69) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL8207221 | 0.81 | TDP1 (0.51) | PTGDR2FFAR1TDP1 | |
| SCHEMBL1549799 | 0.81 | ESR1 (0.61) | — | |
| SCHEMBL4655073 | 0.81 | ELANE (0.56) | PTGDR2TDP1 | |
| SCHEMBL2823002 | 0.81 | PPARD (0.52) | PPARDPPARGPPARAPTGDR2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929567-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | Zealand Pharmaceuticals A/S (DK) | 1999-07-21 | — | — | EP | claimed |
| WO-1998011125-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | ZEALAND PHARMACEUTICALS A/S (DK) | 1998-03-19 | — | — | WO | claimed |
| US-20210188758-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | VTVX HOLDINGS II LLC | 2021-06-24 | — | — | US | disclosed |
| US-10947180-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200215073-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | HIGH POINT PHARMACEUTICALS, LLC | 2020-07-09 | — | — | US | disclosed |
| US-10471066-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2019-11-12 | — | — | US | disclosed |
| US-20180071304-A1 | Phenoxy Acetic Acids and Phenyl Propionic Acids as PPAR Delta Agonists | HIGH POINT PHARMACEUTICALS, LLC | 2018-03-15 | — | — | US | disclosed |
| US-9855274-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170216303-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | HIGH POINT PHARMACEUTICALS, LLC | 2017-08-03 | — | — | US | disclosed |
| US-9663481-B2 | Phenoxy acetic acids and phenyl propionic acids as PPARδ agonists | VTV THERAPEUTICS LLC (US) | 2017-05-30 | — | — | US | disclosed |
| EP-2308976-B2 | Novel herbicide resistance gene | DOW AGROSCIENCES LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2004000315-A1 | PHENYLALKANOIC ACID AND PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-31 | — | — | WO | disclosed |
| EP-1343773-A1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2003072102-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003072100-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
| WO-2002092590-A1 | FURAN AND THIOPHENE DERIVATIVES THAT ACTIVATE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | GLAXO GROUP LIMITED (GB) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002062774-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |
| US-5869602-A | GLUCAGON HAVING LIPOPHILIC SUBSTITUENT ON EPSILON-AMINO GROUP OF LYSINE IN POSITION 30 | NOVO NORDISK A/S (DK) | 1999-02-09 | — | — | US | disclosed |
| EP-0378881-B1 | SYNTHETIC PEPTIDES AND THEIR USE AS UNIVERSAL CARRIERS FOR THE PREPARATION OF IMMUNOGENIC CONJUGATES SUITABLE FOR THE DEVELOPMENT OF SYNTHETIC VACCINES | ENIRICERCHE S.p.A. (IT) | 1993-06-09 | — | — | EP | disclosed |
| EP-0378881-A1 | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines | ENIRICERCHE S.p.A. (IT) | 1990-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10471066-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
| US-20170216303-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
| US-10947180-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
| US-20180071304-A1 | Phenoxy Acetic Acids and Phenyl Propionic Acids as PPAR Delta Agonists | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
| US-20200215073-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
| US-20210188758-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.