Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19759591 | 0.91 | ROCK2 (0.51) | ROCK2GRK2 | |
| SCHEMBL19759703 | 0.89 | ROCK2 (0.53) | ROCK2GRK2 | |
| SCHEMBL19759729 | 0.89 | ROCK2 (0.54) | ROCK2GRK2 | |
| SCHEMBL19759724 | 0.86 | ROCK2 (0.50) | ROCK2GRK2 | |
| SCHEMBL19759722 | 0.85 | ROCK2 (0.53) | ROCK2 | |
| SCHEMBL19759702 | 0.82 | ROCK2 (0.56) | ROCK2GRK2 | |
| SCHEMBL19759622 | 0.80 | ROCK2 (0.59) | ROCK2 | |
| SCHEMBL19759793 | 0.80 | ROCK2 (0.55) | ROCK2 | |
| SCHEMBL19759594 | 0.80 | ROCK2 (0.54) | ROCK2GRK2 | |
| SCHEMBL19759590 | 0.78 | ROCK2 (0.53) | ROCK2GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180000788-A1 | CYCLIC UREAS AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2018-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000788-A1 | CYCLIC UREAS AS INHIBITORS OF ROCK | MYLK, ROCK1, UACA | ROCK2 4/4885GRK2 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.