Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17936450 | 0.85 | EPHX1 (0.62) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL19757996 | 0.84 | EPHX1 (0.60) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL10268244 | 0.82 | EPHX1 (0.65) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL20061880 | 0.82 | EPHX1 (0.51) | EPHX1ALDH1A1MAPTEPHX2MEN1 | |
| SCHEMBL2321232 | 0.82 | EPHX1 (0.65) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL22332323 | 0.82 | ATF4 (0.43) | EPHX1ALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL13459878 | 0.81 | EPHX1 (0.63) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL22332321 | 0.81 | NPSR1 (0.41) | ALDH1A1L3MBTL1HTTRAB9AEPHX2 | |
| SCHEMBL4206232 | 0.81 | EPHX1 (0.63) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 | |
| SCHEMBL307482 | 0.81 | EPHX1 (0.63) | EPHX1ALDH1A1L3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-19 | — | — | US | disclosed |
| US-9932324-B2 | Substituted benzimidazolium compounds useful in the treatment of respiratory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-04-03 | — | — | US | disclosed |
| US-20180009789-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105512-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | TPSD1, TPSAB1, TMSB4X | EPHX1 4135/4885ALDH1A1 2197/4885L3MBTL1 1187/4885 |
| US-20180009789-A1 | SUBSTITUTED BENZIMIDAZOLIUM COMPOUNDS USEFUL IN THE TREATMENT OF RESPIRATORY DISEASES | F12, CKMT1A; CKMT1B, CHRM1 | EPHX1 3508/4885ALDH1A1 928/4885L3MBTL1 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.