SCHEMBL1976480

SCHEMBL1976480

CCCC=CN(C=CCCC)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.39
PPARG P37231 4/20 0.36
TERT O14746 3/20 0.36
PTPN1 P18031 3/20 0.36
PPARD Q03181 3/20 0.36
PPARA Q07869 3/20 0.36
TOP1 P11387 3/20 0.36
MAPT P10636 2/20 0.36
BLM P54132 2/20 0.36
HSD17B10 Q99714 2/20 0.36
FABP4 P15090 2/20 0.36
F7 P08709 2/20 0.36
F3 P13726 2/20 0.36
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1976479 1.00 FFAR3 (0.39) FFAR3PPARGTERTPTPN1PPARD
SCHEMBL20529760 0.87 F7 (0.52) PPARGTERTPTPN1PPARDPPARA
SCHEMBL20529770 0.85 PPARG (0.55) PPARGTERTPTPN1PPARDPPARA
SCHEMBL22558363 0.84 TERT (0.58) PPARGTERTPTPN1PPARDPPARA
SCHEMBL6137570 0.83 PPARG (0.34) PPARGTERTPTPN1PPARDPPARA
SCHEMBL20529762 0.81 FFAR3 (0.43) FFAR3PPARGPPARDPPARAMAPT
SCHEMBL3500945 0.75 CA12 (0.43) MAPTHSD17B10LMNACYP1A2ALOX15
SCHEMBL20529778 0.73 FFAR3 (0.38) FFAR3BLMHSD17B10LMNAALOX15
SCHEMBL20529777 0.73 FFAR3 (0.38) FFAR3BLMHSD17B10LMNAALOX15
SCHEMBL11213104 0.73 TAS1R3 (0.33) PPARGTERTPTPN1PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304622-A1 SHORT APOLIPOPROTEIN E MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2025-10-02 US claimed
CN-119233984-A Short apolipoprotein E mimetic peptides and methods of use thereof 美国政府(由卫生和人类服务部的部长所代表) 2024-12-31 CN claimed
US-20240309065-A1 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2024-09-19 US claimed
EP-4359432-A2 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-05-01 EP claimed
CN-117580857-A APOC-II short mimetic peptides and methods of use 美国政府(由卫生和人类服务部的部长所代表) 2024-02-20 CN claimed
WO-2022271814-A2 SHORT APOC-II MIMETIC PEPTIDES AND METHODS OF USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-12-29 WO claimed
EP-3962933-A1 SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES Dana-Farber Cancer Institute, Inc. (US) 2022-03-09 EP claimed
CN-114026113-A Selective targeting of ubiquitin and ubiquitin-like E1 activating enzymes by structurally stabilized peptides 丹娜法伯癌症研究院 2022-02-08 CN claimed
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz Therapeutics, Inc. 2021-10-21 US claimed
WO-2021127493-A1 STRUCTURALLY-STABILIZED GLUCAGON-LIKE PEPTIDE 1 PEPTIDES AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2021-06-24 WO claimed
US-10774114-B2 Respiratory syncytial virus (RSV) replication inhibitors FONDATION THE ARK (CH) 2020-09-15 US claimed
EP-3606940-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz, LLC (US) 2020-02-12 EP claimed
WO-2018187499-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY BIONIZ, LLC (US) 2018-10-11 WO claimed
US-20260041753-A1 RESPIRATORY SYNCYTIAL VIRUS SURFACE GLYCOPROTEIN PEPTIDES, CONJUGATES, AND USES THEREOF DANA FARBER CANCER INST INC (US) 2026-02-12 US disclosed
EP-4676512-A2 RESPIRATORY SYNCYTIAL VIRUS SURFACE GLYCOPROTEIN PEPTIDES, CONJUGATES, AND USES THEREOF Dana Farber Cancer Institute, Inc. (US) 2026-01-14 EP disclosed
EP-4676938-A2 HENDRA VIRUS AND NIPAH VIRUS SURFACE GLYCOPROTEIN PEPTIDES, CONJUGATES, AND USES THEREOF Dana-Farber Cancer Institute, Inc. (US) 2026-01-14 EP disclosed
US-20100184645-A1 STITCHED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2010-07-22 US disclosed
WO-2010011313-A2 LIGATION OF STAPLED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-01-28 WO disclosed
EP-2142562-A2 STITCHED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-01-13 EP disclosed
WO-2008121767-A2 STITCHED POLYPEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184645-A1 STITCHED POLYPEPTIDES VIP, IAPP, NGLY1 FFAR3 2988/4885PPARG 4770/4885TERT 1744/4885
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY IL2, IL2RA, GMFG FFAR3 4567/4885PPARG 1025/4885TERT 3082/4885
US-20260041753-A1 RESPIRATORY SYNCYTIAL VIRUS SURFACE GLYCOPROTEIN PEPTIDES, CONJUGATES, AND USES THEREOF CETP, HDLBP, NR1H3 FFAR3 2312/4885PPARG 1206/4885TERT 3570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.