SCHEMBL197669

SCHEMBL197669

O=[C]/C=C/c1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
LMNA P02545 1/20 0.57
NFKB1 P19838 2/20 0.55
CDK4 P11802 1/20 0.55
CCND1 P24385 1/20 0.55
JUN P05412 1/20 0.55
NFE2L2 Q16236 1/20 0.55
CA2 P00918 3/20 0.53
CA1 P00915 1/20 0.53
CA4 P22748 1/20 0.53
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
TRPA1 O75762 1/20 0.52
BCHE P06276 1/20 0.48
GUSB P08236 1/20 0.48
CHRNA7 P36544 3/20 0.44
MAPK1 P28482 2/20 0.43
APP P05067 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALPL P05186 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348791 1.00 MAPT (0.57) MAPTLMNANFKB1CDK4CCND1
SCHEMBL3811810 0.84 LMNA (0.41) MAPTLMNANFKB1CDK4CCND1
SCHEMBL16758730 0.83 IAPP (0.59) MAPTLMNANFKB1CDK4CCND1
SCHEMBL2045820 0.78 TRPA1 (0.52) MAPTLMNANFKB1CDK4CCND1
SCHEMBL2045818 0.78 TRPA1 (0.52) MAPTLMNANFKB1CDK4CCND1
SCHEMBL108389 0.78 TRPA1 (0.76) MAPTLMNANFKB1CDK4CCND1
SCHEMBL717976 0.78 TRPA1 (0.76) MAPTLMNANFKB1CDK4CCND1
SCHEMBL7656903 0.76 ALDH1A1 (0.44) MAPTLMNANFKB1JUNNFE2L2
SCHEMBL7660222 0.76 LMNA (0.59) LMNACDK4CCND1TRIM24TRIM33
SCHEMBL9159165 0.76 TTR (0.45) MAPTLMNANFKB1CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645981-A Preparation and application of tobacco-derived hydroxycinnamoyl-coenzyme A quinic acid transferase mutant 江南大学 2024-03-05 CN claimed
CN-117597021-A Method for high-volume production of polyphenols from red lettuce and use thereof 新格诺康植物技术公司 2024-02-23 CN claimed
CN-116240225-A Series tobacco NtHQT gene and application thereof 中国烟草总公司郑州烟草研究院 2023-06-09 CN claimed
CN-116076620-A Application of polyphenol lettuce in animal feed 浙江迦美善植物科技有限公司 2023-05-09 CN claimed
CN-115867670-A Base-modified nucleotides as substrates for TDT-based enzyme nucleic acids 伊鲁米纳新加坡有限公司 2023-03-28 CN claimed
CN-114657238-B Medlar 40K liquid phase chip and application 宁夏农林科学院枸杞科学研究所 2023-03-24 CN claimed
CN-115598251-A Qualitative analysis method for isomers of hydroxybenzoyl quininic acid and hydroxycinnamoyl quininic acid 山东省分析测试中心(CN) 2023-01-13 CN claimed
CN-114085850-A Cloning of aromatic phenol amine synthetic gene cluster in rice and application in disease resistance 海南大学 2022-02-25 CN claimed
CN-111329775-A Isobutyramide derivative and use thereof 福建莲珂科技有限公司 2020-06-26 CN claimed
EP-3116986-A1 HAND SANITIZERS WITH IMPROVED AESTHETICS AND SKIN-CONDITIONING TO ENCOURAGE COMPLIANCE WITH HAND HYGIENE GUIDELINES GOJO Industries, Inc. (US) 2017-01-18 EP claimed
EP-0932612-A4 MANIPULATION OF LIGNIN COMPOSITION IN PLANTS USING A TISSUE-SPECIFIC PROMOTER PURDUE RESEARCH FOUNDATION (US) 2000-11-02 EP claimed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP claimed
US-5985242-A PEPTIDE OF 3 TO 5 D-AMINO ACIDS; MAY BE MODIFIED AT AMINO-AND/OR CARBOXY TERMINUS; FOR TREATMENT OF AMYLOIDOSIS, ALZHEIMER'S DISEASE PRAECIS PHARMACEUTICALS, INC. (US) 1999-11-16 US claimed
EP-0932612-A1 MANIPULATION OF LIGNIN COMPOSITION IN PLANTS USING A TISSUE-SPECIFIC PROMOTER Purdue Research Foundation (US) 1999-08-04 EP claimed
EP-0929574-A1 MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS Praecis Pharmaceuticals Incorporated (US) 1999-07-21 EP claimed
EP-0581980-B1 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid NESTLE SA (CH) 1999-03-03 EP claimed
WO-1998008868-A9 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS 1998-05-28 WO claimed
WO-1998008868-A1 MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS PRAECIS PHARMACEUTICALS INCORPORATED (US) 1998-03-05 WO claimed
WO-1998003535-A1 MANIPULATION OF LIGNIN COMPOSITION IN PLANTS USING A TISSUE-SPECIFIC PROMOTER PURDUE RESEARCH FOUNDATION (US) 1998-01-29 WO claimed
EP-0581980-A1 3- and/or 4-substituted derivatives of quinic acid and process to prepare 3- and/or 4-substituted derivatives of quinic acid SOCIETE DES PRODUITS NESTLE S.A. (CH) 1994-02-09 EP claimed