Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.36 |
| ▸ | CASR | P41180 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21913657 | 0.79 | AR (0.39) | — | |
| SCHEMBL20180730 | 0.78 | ALKBH5 (0.39) | ALKBH5NOTUMSOS1HTR2AHTR2C | |
| SCHEMBL19767128 | 0.78 | ACACB (0.38) | ALKBH5NOTUMSOS1HTR2AHTR2C | |
| SCHEMBL13122994 | 0.76 | AR (0.49) | ALKBH5NOTUMHTR2AHTR2CHTR2B | |
| SCHEMBL16523153 | 0.75 | KDM4E (0.42) | ALKBH5NOTUM | |
| SCHEMBL13123030 | 0.75 | KDM4E (0.42) | ALKBH5NOTUM | |
| SCHEMBL21534772 | 0.75 | GRM4 (0.43) | ACACB | |
| SCHEMBL28166708 | 0.74 | AR (0.48) | ALKBH5NOTUMHTR2AHTR2CHTR2B | |
| SCHEMBL28057536 | 0.73 | SOS1 (0.48) | ALKBH5NOTUMSOS1 | |
| SCHEMBL14414421 | 0.72 | PDK2 (0.44) | ALKBH5NOTUMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180009754-A1 | ANTHELMINTIC COMPOUNDS, COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL, INC. (US) | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009754-A1 | ANTHELMINTIC COMPOUNDS, COMPOSITIONS AND METHOD OF USING THEREOF | CYP8B1, CYP2C8, CYP2B6 | ALKBH5 2049/4885NOTUM 451/4885SOS1 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.