Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 9/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13122994 | 0.80 | AR (0.49) | NOTUMSIRT6ALKBH5MEN1KMT2A | |
| SCHEMBL28166708 | 0.79 | AR (0.48) | NOTUMSIRT6ALKBH5MEN1KMT2A | |
| SCHEMBL14414247 | 0.78 | NOTUM (0.43) | NOTUMSIRT6ALKBH5DPP4 | |
| SCHEMBL4412651 | 0.78 | NOTUM (0.63) | NOTUMALKBH5 | |
| SCHEMBL5537698 | 0.77 | NOTUM (0.50) | NOTUMHRH4CYP3A4 | |
| SCHEMBL21448004 | 0.77 | SIRT6 (0.61) | SOS1SIRT6ALKBH5MEN1KMT2A | |
| SCHEMBL13123141 | 0.76 | NOTUM (0.49) | SOS1NOTUMALKBH5DPP4 | |
| SCHEMBL12059104 | 0.76 | MAPT (0.49) | SOS1NOTUMSIRT6MEN1CYP1A2 | |
| SCHEMBL30822010 | 0.76 | MAPT (0.49) | SOS1NOTUMSIRT6MEN1CYP1A2 | |
| SCHEMBL11627069 | 0.76 | ADRB1 (0.65) | SOS1ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452238-A | Bicyclic derivatives containing a pyrimidine ring and process for preparing the same | YUHAN CORP | 2016-03-30 | — | — | CN | disclosed |