Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | S100B | P04271 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13122994 | 0.98 | AR (0.49) | ARHPGDHTR2AHTR2CHTR2B | |
| SCHEMBL21448004 | 0.85 | SIRT6 (0.61) | SIRT6MEN1KMT2ASMN1; SMN2ALKBH5 | |
| SCHEMBL30822010 | 0.83 | MAPT (0.49) | HPGDHTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL11627069 | 0.83 | ADRB1 (0.65) | HTR2CALKBH5PDK2ALDH1A1MAPT | |
| SCHEMBL12059104 | 0.83 | MAPT (0.49) | HPGDHTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL14414421 | 0.81 | PDK2 (0.44) | NOTUMALKBH5PDK2MAPTHTT | |
| SCHEMBL6233708 | 0.80 | USP30 (0.44) | ARHTR2AHTR2CHTR2BSIRT6 | |
| SCHEMBL28243473 | 0.79 | NOTUM (0.41) | NOTUMALKBH5GAA | |
| SCHEMBL2012912 | 0.79 | HTT (0.59) | ARSIRT6NOTUMLMNAMEN1 | |
| SCHEMBL12875602 | 0.79 | AR (0.48) | ARHPGDSIRT6NOTUMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999481-A | Processes and intermediates for preparing C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2017-08-01 | — | — | CN | disclosed |