Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 8/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19767311 | 0.92 | HCRTR1 (0.43) | MC1RHCRTR1HCRTR2P2RY1P2RX7 | |
| SCHEMBL17799730 | 0.86 | HCRTR1 (0.53) | MC1RHCRTR1HCRTR2P2RX7 | |
| SCHEMBL17799720 | 0.85 | GRM5 (0.45) | MC1RHCRTR1HCRTR2 | |
| SCHEMBL17799746 | 0.83 | MC1R (0.45) | MC1RHCRTR1HCRTR2P2RX7 | |
| SCHEMBL17799638 | 0.83 | HCRTR1 (0.54) | MC1RHCRTR1HCRTR2P2RX7 | |
| SCHEMBL17799631 | 0.82 | HCRTR1 (0.41) | MC1RHCRTR1HCRTR2P2RX7 | |
| SCHEMBL17799752 | 0.81 | MC1R (0.42) | MC1RHCRTR1 | |
| SCHEMBL17799646 | 0.81 | MC1R (0.45) | MC1RHCRTR1P2RX7 | |
| SCHEMBL19775167 | 0.81 | HCRTR1 (0.46) | MC1RHCRTR1P2RX7 | |
| SCHEMBL16371864 | 0.81 | HCRTR1 (0.46) | MC1RHCRTR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |