SCHEMBL17799752

SCHEMBL17799752

Cc1nccnc1C(=O)N[C@H]1CC[C@H]1c1ccc(F)cc1F

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MC1R Q01726 11/20 0.42
▸ GPR6 P46095 1/20 0.41
▸ HCRTR1 O43613 3/20 0.39
▸ CNR1 P21554 3/20 0.37
▸ CNR2 P34972 3/20 0.37
▸ FPR1 P21462 1/20 0.37
▸ FPR2 P25090 1/20 0.37
▸ TAS1R3 Q7RTX0 1/20 0.37
▸ TAS1R1 Q7RTX1 1/20 0.37
▸ TAS1R2 Q8TE23 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17799720 0.87 GRM5 (0.45) MC1RGPR6HCRTR1
SCHEMBL17799755 0.86 HCRTR1 (0.41) MC1RHCRTR1FPR1FPR2TAS1R3
SCHEMBL17799730 0.85 HCRTR1 (0.53) MC1RGPR6HCRTR1
SCHEMBL17799664 0.84 MC1R (0.43) MC1RHCRTR1CNR1CNR2TAS1R3
SCHEMBL17799638 0.82 HCRTR1 (0.54) MC1RHCRTR1
SCHEMBL17799746 0.82 MC1R (0.45) MC1RHCRTR1FPR1FPR2
SCHEMBL17799646 0.81 MC1R (0.45) MC1RHCRTR1FPR1FPR2
SCHEMBL19767308 0.81 MC1R (0.43) MC1RHCRTR1
SCHEMBL17799631 0.81 HCRTR1 (0.41) MC1RHCRTR1CNR1CNR2TAS1R3
SCHEMBL19767311 0.81 HCRTR1 (0.43) MC1RHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 — — US disclosed
EP-3019476-B1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-01-17 — — EP disclosed
US-9867371-B2 4-membered ring carboxamides used as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2018-01-16 — — US disclosed
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2016-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157485-A1 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES TUBA3C, DDT, CYCS MC1R 2554/4885GPR6 2014/4885HCRTR1 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback