Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.43 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371864 | 1.00 | HCRTR1 (0.46) | HCRTR1ACKR3MC1RKDM4EMEN1 | |
| SCHEMBL17799632 | 0.86 | EGFR (0.46) | HCRTR1ACKR3MC1RMEN1KMT2A | |
| SCHEMBL17799664 | 0.86 | MC1R (0.43) | HCRTR1ACKR3MC1RP2RX7 | |
| SCHEMBL16212014 | 0.84 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL16220919 | 0.84 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL16212016 | 0.84 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL17799631 | 0.84 | HCRTR1 (0.41) | HCRTR1MC1RKDM4EKMT2AP2RX7 | |
| SCHEMBL19767311 | 0.84 | HCRTR1 (0.43) | HCRTR1MC1RP2RX7 | |
| SCHEMBL17799693 | 0.84 | TAS1R3 (0.47) | HCRTR1MC1R | |
| SCHEMBL17799646 | 0.83 | MC1R (0.45) | HCRTR1MC1RP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019476-B1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-17 | — | — | EP | disclosed |