Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.75 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.50 |
| ▸ | GPR3 | P46089 | 5/20 | 0.48 |
| ▸ | GPR6 | P46095 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17702684 | 0.92 | P2RY6 (0.64) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL19927824 | 0.87 | P2RY6 (0.78) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL14176751 | 0.86 | MEN1 (0.61) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL16974373 | 0.86 | P2RY6 (1.00) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL16346688 | 0.86 | P2RY6 (0.79) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL19787877 | 0.85 | P2RY6 (0.71) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL31756958 | 0.84 | P2RY6 (0.69) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL22204520 | 0.84 | P2RY6 (0.69) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| SCHEMBL21878583 | 0.83 | P2RY6 (0.67) | P2RY6ITPR1P2RY2HTR3AHRH3 | |
| Tetramethylrhodamine SCHEMBL29838750 | 0.82 | P2RY6 (0.67) | P2RY6ITPR1P2RY2HTR3AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11859019-B2 | Bicyclic peptidyl inhibitor of tumor necrosis factor-alpha | OHIO STATE INNOVATION FOUNDATION (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230173018-A1 | CASPOFUNGIN DERIVATIVES AND ASSAYS FOR EVALUATING ANTIFUNGAL TREATMENT EFFICACY | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2023-06-08 | — | — | US | disclosed |
| US-20180030094-A1 | CHEMICAL SYNTHESIS AND SCREENING OF BICYCLIC PEPTIDE LIBRARIES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-01 | — | — | US | disclosed |
| US-9868767-B2 | Chemical synthesis and screening of bicyclic peptide libraries | OHIO STATE INNOVATION FOUNDATION (US) | 2018-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11859019-B2 | Bicyclic peptidyl inhibitor of tumor necrosis factor-alpha | NFKBIA, TNFRSF1A, NFATC1 | P2RY6 4178/4885ITPR1 2759/4885P2RY2 4066/4885 |
| US-20230173018-A1 | CASPOFUNGIN DERIVATIVES AND ASSAYS FOR EVALUATING ANTIFUNGAL TREATMENT EFFICACY | ERG28, CASP1, CASP7 | P2RY6 4342/4885ITPR1 2766/4885P2RY2 4565/4885 |
| US-20180030094-A1 | CHEMICAL SYNTHESIS AND SCREENING OF BICYCLIC PEPTIDE LIBRARIES | BAD, VIP, SSB | P2RY6 3704/4885ITPR1 3714/4885P2RY2 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.