SCHEMBL19767973

SCHEMBL19767973

CP(=O)(c1ccc2ccccc2c1)c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 3/20 0.43
ACP3 P15309 2/20 0.41
CTSG P08311 1/20 0.41
LMNA P02545 2/20 0.38
ESR1 P03372 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
PLK1 P53350 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 3/20 0.37
PTK2B Q14289 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
PTPN1 P18031 1/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3787100 0.84 ESR1 (0.48) ACP3LMNAESR1KDM4EPOLB
SCHEMBL13002721 0.83 CMA1 (0.44) CMA1ACP3CTSGLMNAKDM4E
SCHEMBL18085206 0.82 ESR1 (0.48) LMNAESR1NPC1RAB9AL3MBTL1
SCHEMBL19743195 0.82 KDM4E (0.46) ACP3LMNAKDM4EPOLBPLK1
SCHEMBL19849794 0.82 CMA1 (0.32) CMA1ACP3CTSGALDH1A1MAPT
SCHEMBL14375087 0.80 KDM4E (0.41) CMA1ACP3CTSGLMNAESR1
SCHEMBL134309 0.80 LMNA (0.41) CMA1ACP3CTSGLMNAKDM4E
SCHEMBL14339291 0.80 LMNA (0.41) CMA1ACP3CTSGLMNAKDM4E
SCHEMBL14339288 0.80 LMNA (0.41) CMA1ACP3CTSGLMNAKDM4E
SCHEMBL9762864 0.78 ESR1 (0.55) LMNAESR1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed
US-20180019407-A1 PHENANTHROLINE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT TORAY INDUSTRIES, INC (JP) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019407-A1 PHENANTHROLINE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT SUN2, PAH, FARS2 CMA1 3788/4885ACP3 3837/4885CTSG 3138/4885
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 CMA1 3704/4885ACP3 4726/4885CTSG 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.