SCHEMBL9762864

SCHEMBL9762864

CP(=O)(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.55
HPGD P15428 2/20 0.46
ALDH1A1 P00352 3/20 0.45
CYP3A4 P08684 2/20 0.45
HSD17B10 Q99714 2/20 0.45
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
MAPT P10636 1/20 0.43
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2A6 P11509 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
GPR84 Q9NQS5 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18085206 0.96 ESR1 (0.48) ESR1HPGDALDH1A1CYP3A4HSD17B10
SCHEMBL21874407 0.89 CYP2A6 (0.50) ESR1HPGDALDH1A1CYP3A4HSD17B10
SCHEMBL13417802 0.83 CYP2A6 (0.44) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL15566288 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL21503905 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL14339277 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL14339280 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL31212637 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL30544386 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1
SCHEMBL14339279 0.81 ALDH1A1 (0.47) HPGDALDH1A1CYP3A4HSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019198806-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2019-10-17 WO disclosed
US-20160240793-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LG CHEM, LTD. (KR) 2016-08-18 US disclosed
US-20160233431-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LG CHEM, LTD. (KR) 2016-08-11 US disclosed
US-20160233432-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LG CHEM, LTD. (KR) 2016-08-11 US disclosed
US-5068425-A Nervous system disorders, intermediates for drugs and as enantiomorphs SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240793-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CRY1, CRY2, NR2E3 ESR1 19/4885HPGD 1235/4885ALDH1A1 252/4885
US-20160233431-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CRY1, CRY2, NR2E3 ESR1 19/4885HPGD 1235/4885ALDH1A1 252/4885
US-20160233432-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CRY1, CRY2, NR2E3 ESR1 19/4885HPGD 1235/4885ALDH1A1 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.